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Protein Overview: EG10708

General Information:
Name(s) found: pheP / EG10708 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • phenylalanine transporter / Phenylalanine-specific permease [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    plasma membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    amino acid transport [IEA]
    transport [IEA]
    Molecular Function: amino acid transmembrane transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNASTVSED TASNQEPTLH RGLHNRHIQL IALGGAIGTG LFLGIGPAIQ MAGPAVLLGY  60
   61 GVAGIIAFLI MRQLGEMVVE EPVSGSFAHF AYKYWGPFAG FLSGWNYWVM FVLVGMAELT 120
  121 AAGIYMQYWF PDVPTWIWAA AFFIIINAVN LVNVRLYGET EFWFALIKVL AIIGMIGFGL 180
  181 WLLFSGHGGE KASIDNLWRY GGFFATGWNG LILSLAVIMF SFGGLELIGI TAAEARDPEK 240
  241 SIPKAVNQVV YRILLFYIGS LVVLLALYPW VEVKSNSSPF VMIFHNLDSN VVASALNFVI 300
  301 LVASLSVYNS GVYSNSRMLF GLSVQGNAPK FLTRVSRRGV PINSLMLSGA ITSLVVLINY 360
  361 LLPQKAFGLL MALVVATLLL NWIMICLAHL RFRAAMRRQG RETQFKALLY PFGNYLCIAF 420
  421 LGMILLLMCT MDDMRLSAIL LPVWIVFLFM AFKTLRRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..458] FFAS03 1.19 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • amine transmembrane transporter activity
    		•  5.15069657292327 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  4.54752581624334 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  4.39427743642027 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  4.356142166703 bayes_pls_golite062009
  • transporter activity
    		•  3.46503611631839 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.34431027577801 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.08398439124803 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.98812190037621 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.96577701947757 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.89542769737674 bayes_pls_golite062009
  • organic acid:sodium symporter activity
    		•  1.82263833070018 bayes_pls_golite062009
  • L-amino acid transmembrane transporter activity
    		•  1.79964917042361 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79923665576923 bayes_pls_golite062009
  • neutral amino acid transmembrane transporter activity
    		•  1.71764370341895 bayes_pls_golite062009
  • monoamine transmembrane transporter activity
    		•  1.59349600647168 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.37015067735708 bayes_pls_golite062009
  • symporter activity
    		•  1.31198147603118 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  1.31198147603118 bayes_pls_golite062009
  • solute:sodium symporter activity
    		•  0.868753445363102 bayes_pls_golite062009
  • neurotransmitter:sodium symporter activity
    		•  0.658077875061275 bayes_pls_golite062009
  • binding
    		•  0.299468111884938 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle