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Protein Overview: EG11056

General Information:
Name(s) found: umuC / EG11056 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • translesion error-prone DNA polymerase V subunit; DNA polymerase activity / Translesion DNA polymerase V subunit, DNA polymerizing subunit; error-prone repair; induced mutagenesis protein; DNA damage checkpoint effector; intrinsic AP lyase activity; DNA exonuclease activity [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 422 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: DNA repair [IEA]
    DNA-dependent DNA replication [IEA]
    SOS response [IEA]
    response to DNA damage stimulus [IEA][IEPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    DNA binding [IEA]
    DNA-directed DNA polymerase activity [IEA]
    protein binding [IPILink to PubMed article]
    damaged DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFALCDVNAF YASCETVFRP DLWGKPVVVL SNNDGCVIAR NAEAKALGVK MGDPWFKQKD  60
   61 LFRRCGVVCF SSNYELYADM SNRVMSTLEE LSPRVEIYSI DEAFCDLTGV RNCRDLTDFG 120
  121 REIRATVLQR THLTVGVGIA QTKTLAKLAN HAAKKWQRQT GGVVDLSNLE RQRKLMSALP 180
  181 VDDVWGIGRR ISKKLDAMGI KTVLDLADTD IRFIRKHFNV VLERTVRELR GEPCLQLEEF 240
  241 APTKQEIICS RSFGERITDY PSMRQAICSY AARAAEKLRS EHQYCRFIST FIKTSPFALN 300
  301 EPYYGNSASV KLLTPTQDSR DIINAATRSL DAIWQAGHRY QKAGVMLGDF FSQGVAQLNL 360
  361 FDDNAPRPGS EQLMTVMDTL NAKEGRGTLY FAGQGIQQQW QMKRAMLSPR YTTRSSDLLR 420
  421 VK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..362] PSI-BLAST 59.522879 oxoG-modified Insertion Ternary Complex
    2 View Details [363..422] MSA 6.356995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.518931870161593 bayes_pls_golite062009
  • transferase activity
    		•  0.35636561630516 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.32441153240842 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.29860211454192 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.0603497936698201 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.0602875211585996 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle