YRC Public Data Repository - Protein Structure Prediction

Protein:	EG11056
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	422 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG11056.

Description	E-value	Query Range	Subject Range
gi\|24051469, gi\|... - gi\|24112571\|ref\|NP_707081.1\| DNA polymerase V subunit UmuC [Shigella flexneri 2a str. 301], gi\|24051... gi\|30040949, gi\|... - gi\|30062701\|ref\|NP_836872.1\| DNA polymerase V subunit UmuC [Shigella flexneri 2a str. 2457T], gi\|300... gi\|110805183, gi... - gi\|110805183\|ref\|YP_688703.1\| DNA polymerase V subunit UmuC [Shigella flexneri 5 str. 8401], gi\|1106...	426.0	[0..1]	[422..1]
gi\|91210397, gi\|... - gi\|91210397\|ref\|YP_540383.1\| DNA polymerase V subunit UmuC [Escherichia coli UTI89], gi\|91071971\|gb\|... gi\|237705139, gi... - gi\|237705139\|ref\|ZP_04535620.1\| UmuC protein [Escherichia sp. 3_2_53FAA], gi\|226899896\|gb\|EEH86155.1... gi\|218364877, gi... - gi\|218558108\|ref\|YP_002391021.1\| DNA polymerase V subunit UmuC [Escherichia coli S88], gi\|218364877\|...	426.0	[0..1]	[422..1]
gi\|83587328, gi\|... - gi\|83587328\|ref\|ZP_00925956.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair...	426.0	[0..1]	[422..1]
gi\|188494421, gi... - gi\|75511635\|ref\|ZP_00734282.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair... gi\|192955505, gi... - gi\|75233919\|ref\|ZP_00718379.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair...	426.0	[0..1]	[422..1]
gi\|117623398, gi... - gi\|117623398\|ref\|YP_852311.1\| DNA polymerase V subunit UmuC [Escherichia coli APEC O1], gi\|115512522...	426.0	[0..1]	[422..1]
gi\|254592061, gi... - gi\|254792661\|ref\|YP_003077498.1\| DNA polymerase V, subunit C [Escherichia coli O157:H7 str. TW14359]... gi\|208732550, gi... - gi\|208815902\|ref\|ZP_03257081.1\| protein UmuC [Escherichia coli O157:H7 str. EC4045], gi\|208732550\|gb... gi\|208728509, gi... - gi\|208808708\|ref\|ZP_03251045.1\| protein UmuC [Escherichia coli O157:H7 str. EC4206], gi\|208728509\|gb... gi\|195938839 - gi\|195938839\|ref\|ZP_03084221.1\| DNA polymerase V subunit UmuC [Escherichia coli O157:H7 str. EC4024] gi\|189372493, gi... - gi\|189372493\|gb\|EDU90909.1\| protein UmuC [Escherichia coli O157:H7 str. EC869], gi\|168787685\|ref\|ZP_... gi\|15830933, gi\|... - gi\|15830933\|ref\|NP_309706.1\| DNA polymerase V subunit UmuC [Escherichia coli O157:H7 str. Sakai], gi... gi\|217318447, gi... - gi\|217328020\|ref\|ZP_03444102.1\| protein UmuC [Escherichia coli O157:H7 str. TW14588], gi\|217318447\|g... gi\|209400560, gi... - gi\|209400560\|ref\|YP_002270124.1\| protein UmuC [Escherichia coli O157:H7 str. EC4115], gi\|209161960\|g... gi\|208737807, gi... - gi\|208822322\|ref\|ZP_03262641.1\| protein UmuC [Escherichia coli O157:H7 str. EC4042], gi\|208737807\|gb... gi\|168752765, gi... - gi\|188013532\|gb\|EDU51654.1\| protein UmuC [Escherichia coli O157:H7 str. EC4113], gi\|168752765\|ref\|ZP... gi\|209772706, gi... - pir\|\|G90838 UmuC protein [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952), gi\|... gi\|188999983, gi... - gi\|188999983\|gb\|EDU68969.1\| protein UmuC [Escherichia coli O157:H7 str. EC4076], gi\|168782542\|ref\|ZP... gi\|168771075, gi... - gi\|189360080\|gb\|EDU78499.1\| protein UmuC [Escherichia coli O157:H7 str. EC4486], gi\|168771075\|ref\|ZP... gi\|15830933, gi\|... - gi\|15830933\|ref\|NP_309706.1\| DNA polymerase IV [Escherichia coli O157:H7], gi\|13361143\|dbj\|BAB35102.... gi\|189364859, gi... - gi\|189364859\|gb\|EDU83275.1\| protein UmuC [Escherichia coli O157:H7 str. EC4501], gi\|168765429\|ref\|ZP... gi\|168756549, gi... - gi\|189356339\|gb\|EDU74758.1\| protein UmuC [Escherichia coli O157:H7 str. EC4401], gi\|168756549\|ref\|ZP...	425.0	[0..1]	[422..1]
gi\|157160687, gi... - gi\|75195337\|ref\|ZP_00705407.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair...	425.0	[0..1]	[422..1]
gi\|25300614 - pir\|\|G85696 SOS mutagenesis and repair [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|12514881, gi\|... - gi\|15801406\|ref\|NP_287423.1\| DNA polymerase V subunit UmuC [Escherichia coli O157:H7 EDL933], gi\|125...	425.0	[0..1]	[422..1]
gi\|148126 - gi\|148126\|gb\|AAA24729.1\| UmuC protein	424.0	[0..1]	[422..1]
gi\|26247497, gi\|... - gi\|26247497\|ref\|NP_753537.1\| DNA polymerase V subunit UmuC [Escherichia coli CFT073], gi\|26107898\|gb...	423.0	[0..1]	[422..1]

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Predicted Domain #1

Region A:
Residues: [1-362]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFALCDVNAF YASCETVFRP DLWGKPVVVL SNNDGCVIAR NAEAKALGVK MGDPWFKQKD  60
   61 LFRRCGVVCF SSNYELYADM SNRVMSTLEE LSPRVEIYSI DEAFCDLTGV RNCRDLTDFG 120
  121 REIRATVLQR THLTVGVGIA QTKTLAKLAN HAAKKWQRQT GGVVDLSNLE RQRKLMSALP 180
  181 VDDVWGIGRR ISKKLDAMGI KTVLDLADTD IRFIRKHFNV VLERTVRELR GEPCLQLEEF 240
  241 APTKQEIICS RSFGERITDY PSMRQAICSY AARAAEKLRS EHQYCRFIST FIKTSPFALN 300
  301 EPYYGNSASV KLLTPTQDSR DIINAATRSL DAIWQAGHRY QKAGVMLGDF FSQGVAQLNL 360
  361 FD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.522879
Match:	2asdA
Description:	oxoG-modified Insertion Ternary Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.518931870161593	bayes_pls_golite062009
transferase activity	0.35636561630516	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.32441153240842	bayes_pls_golite062009
nucleotidyltransferase activity	0.29860211454192	bayes_pls_golite062009
DNA polymerase activity	0.0603497936698201	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.0602875211585996	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [363-422]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNAPRPGSEQ LMTVMDTLNA KEGRGTLYFA GQGIQQQWQM KRAMLSPRYT TRSSDLLRVK  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: