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Protein Overview: EG10857

General Information:
Name(s) found: rnc / EG10857 [EcoGene]
Description(s) found:
Found 6 descriptions.
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  • RNase III / RNase III; cleaves double-stranded RNA [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 226 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    intracellular [IEA]
    Biological Process: rRNA catabolic process [IEA]
    RNA processing [IEA]
    mRNA processing [IEA]
    rRNA processing [IEA]
    Molecular Function: protein binding [IPILink to PubMed article]
    RNA binding [IEA]
    ribonuclease III activity [IEA]
    double-stranded RNA binding [IEA]
    endonuclease activity [IEA]
    nuclease activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPIVINRLQ RKLGYTFNHQ ELLQQALTHR SASSKHNERL EFLGDSILSY VIANALYHRF  60
   61 PRVDEGDMSR MRATLVRGNT LAELAREFEL GECLRLGPGE LKSGGFRRES ILADTVEALI 120
  121 GGVFLDSDIQ TVEKLILNWY QTRLDEISPG DKQKDPKTRL QEYLQGRHLP LPTYLVVQVR 180
  181 GEAHDQEFTI HCQVSGLSEP VVGTGSSRRK AEQAAAEQAL KKLELE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..226] PSI-BLAST 48.0 RNase III endonuclease catalytic domain; RNase III, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  2.103878681691 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.02847548000256 bayes_pls_golite062009
  • endonuclease activity
    		•  1.52328576888271 bayes_pls_golite062009
  • binding
    		•  1.36306903445995 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.33734225890407 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  0.80785216315429 bayes_pls_golite062009
  • catalytic activity
    		•  0.328884095744829 bayes_pls_golite062009
  • protein binding
    		•  0.018276859224266 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle