YRC Public Data Repository - Protein Structure Prediction

Protein:	EG10857
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	226 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG10857.

Description	E-value	Query Range	Subject Range
gi\|62128779, gi\|... - gi\|62181146\|ref\|YP_217563.1\| ribonuclease III [Salmonella enterica subsp. enterica serovar Choleraes...	251.0	[0..1]	[226..20]
RNC_SALCH - Ribonuclease 3 OS=Salmonella choleraesuis GN=rnc PE=3 SV=2 RNC_SALCH - Ribonuclease 3 OS=Salmonella choleraesuis (strain SC-B67) GN=rnc PE=3 SV=2 RNC_SALCH - Ribonuclease 3 OS=Salmonella choleraesuis GN=rnc PE=3 SV=2	248.0	[0..1]	[226..1]
gi\|153839958, gi... - gi\|153839958\|ref\|ZP_01992625.1\| ribonuclease III [Vibrio parahaemolyticus AQ3810], gi\|149746517\|gb\|E... RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus GN=rnc PE=3 SV=1 RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=rnc PE=3 SV=1	243.0	[0..3]	[225..2]
gi\|91227852, gi\|... - gi\|91227852\|ref\|ZP_01262025.1\| ribonuclease III [Vibrio alginolyticus 12G01], gi\|91188362\|gb\|EAS7465...	242.0	[0..3]	[225..2]
gi\|194538394, gi... - gi\|75854070\|ref\|ZP_00761790.1\| COG0571: dsRNA-specific ribonuclease [Vibrio sp. Ex25], gi\|254230524\|...	242.0	[0..3]	[225..2]
gi\|197335272, gi... - gi\|197335272\|ref\|YP_002156886.1\| ribonuclease III [Vibrio fischeri MJ11], gi\|197316762\|gb\|ACH66209.1... RNC_VIBF1 - Ribonuclease 3 OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=rnc PE=3 SV=1	242.0	[0..1]	[223..1]
RNC_VIBTL - Ribonuclease 3 OS=Vibrio tasmaniensis (strain LGP32) GN=rnc PE=3 SV=1 gi\|84376758, gi\|... - gi\|84390104\|ref\|ZP_00991366.1\| ribonuclease III [Vibrio splendidus 12B01], gi\|84376758\|gb\|EAP93633.1... gi\|86146359, gi\|... - gi\|86146359\|ref\|ZP_01064683.1\| ribonuclease III [Vibrio sp. MED222], gi\|85835838\|gb\|EAQ53972.1\| ribo...	240.0	[0..3]	[225..2]
gi\|126509385, gi... - gi\|153820073\|ref\|ZP_01972740.1\| ribonuclease III [Vibrio cholerae NCTC 8457], gi\|126509385\|gb\|EAZ719... gi\|254845291, gi... - gi\|254849586\|ref\|ZP_05238936.1\| ribonuclease III [Vibrio cholerae MO10], gi\|254845291\|gb\|EET23705.1\|... RNC_VIBCH - Ribonuclease 3 OS=Vibrio cholerae GN=rnc PE=3 SV=1 gi\|229512326, gi... - gi\|229512326\|ref\|ZP_04401805.1\| ribonuclease III [Vibrio cholerae B33], gi\|229352291\|gb\|EEO17232.1\| ... RNC_VIBCM - Ribonuclease 3 OS=Vibrio cholerae serotype O1 (strain M66-2) GN=rnc PE=3 SV=1 gi\|229519462, gi... - gi\|229519462\|ref\|ZP_04408905.1\| ribonuclease III [Vibrio cholerae RC9], gi\|229344151\|gb\|EEO09126.1\| ... gi\|229507479, gi... - gi\|229507479\|ref\|ZP_04396984.1\| ribonuclease III [Vibrio cholerae BX 330286], gi\|229354984\|gb\|EEO199... gi\|229606984, gi... - gi\|229606984\|ref\|YP_002877632.1\| ribonuclease III [Vibrio cholerae MJ-1236], gi\|229369639\|gb\|ACQ6006... RNC_VIBCH - Ribonuclease 3 OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=rnc PE=3 ... gi\|153222435, gi... - gi\|153222435\|ref\|ZP_01953169.1\| ribonuclease III [Vibrio cholerae MAK 757], gi\|124118872\|gb\|EAY37615... gi\|121590982, gi... - gi\|121590982\|ref\|ZP_01678301.1\| ribonuclease III [Vibrio cholerae 2740-80], gi\|121547159\|gb\|EAX57288...	239.0	[0..4]	[225..3]
RNC_SHEAM - Ribonuclease 3 OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=rnc PE=3 SV=1	238.0	[0..1]	[223..1]
gi\|75829322, gi\|... - gi\|75829322\|ref\|ZP_00758629.1\| COG0571: dsRNA-specific ribonuclease [Vibrio cholerae MO10], gi\|11618...	238.0	[0..6]	[225..1]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPIVINRLQ RKLGYTFNHQ ELLQQALTHR SASSKHNERL EFLGDSILSY VIANALYHRF  60
   61 PRVDEGDMSR MRATLVRGNT LAELAREFEL GECLRLGPGE LKSGGFRRES ILADTVEALI 120
  121 GGVFLDSDIQ TVEKLILNWY QTRLDEISPG DKQKDPKTRL QEYLQGRHLP LPTYLVVQVR 180
  181 GEAHDQEFTI HCQVSGLSEP VVGTGSSRRK AEQAAAEQAL KKLELE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1o0wA
Description:	RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	2.103878681691	bayes_pls_golite062009
endoribonuclease activity	2.02847548000256	bayes_pls_golite062009
endonuclease activity	1.52328576888271	bayes_pls_golite062009
binding	1.36306903445995	bayes_pls_golite062009
nucleic acid binding	1.33734225890407	bayes_pls_golite062009
double-stranded RNA binding	0.80785216315429	bayes_pls_golite062009
catalytic activity	0.328884095744829	bayes_pls_golite062009
protein binding	0.018276859224266	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: