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Protein Overview: gi|1827521, gi|1...

General Information:
Name(s) found: gi|85543961 [NCBI NR]
gi|2905618 [NCBI NR]
gi|1827645 [NCBI NR]
gi|1827521 [NCBI NR]
gi|15988303 [NCBI NR]
gi|157835209 [NCBI NR]
gi|157831476 [NCBI NR]
gi|118137857 [NCBI NR]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • gi|85543961|pdb|1Y6K|L Chain L, Crystal Structure Of Human Il-10 Complexed With The Soluble Il-10r1 Chain [NCBI NR]
  • gi|2905618|gb|AAC03534.1| interleukin 10 [Homo sapiens] [NCBI NR]
  • gi|1827645|pdb|1INR| Chain , Cytokine Synthesis [NCBI NR]
  • gi|1827521|pdb|2ILK| Chain , Crystal Structure Of Human Interleukin-10 At 1.6 Angstroms Resolution [NCBI NR]
  • gi|15988303|pdb|1J7V|L Chain L, Human Il-10 IL-10r1 Complex [NCBI NR]
  • gi|157835209|pdb|2ILK|A Chain A, Crystal Structure Of Human Interleukin-10 At 1.6 Angstroms Resolution [NCBI NR]
  • gi|157831476|pdb|1INR|A Chain A, Cytokine Synthesis [NCBI NR]
  • gi|118137857|pdb|2H24|A Chain A, Crystal Structure Of Human Il-10 [NCBI NR]
    • Organism: Homo sapiens
    Length: 160 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPGQGTQSEN SCTHFPGNLP NMLRDLRDAF SRVKTFFQMK DQLDNLLLKE SLLEDFKGYL  60
   61 GCQALSEMIQ FYLEEVMPQA ENQDPDIKAH VNSLGENLKT LRLRLRRCHR FLPCENKSKA 120
  121 VEQVKNAFNK LQEKGIYKAM SEFDIFINYI EAYMTMKIRN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|1827521, gi|1...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] PSI-BLAST 55.30103 CYTOKINE SYNTHESIS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytokine receptor binding
    		•  6.47223189691244 bayes_pls_golite062009
  • cytokine activity
    		•  6.38439864086716 bayes_pls_golite062009
  • receptor binding
    		•  5.3304255990112 bayes_pls_golite062009
  • interleukin-10 receptor binding
    		•  4.72567047009114 bayes_pls_golite062009
  • growth factor activity
    		•  4.19013747697608 bayes_pls_golite062009
  • protein binding
    		•  3.26483713001551 bayes_pls_golite062009
  • hormone activity
    		•  2.52921243340076 bayes_pls_golite062009
  • binding
    		•  2.48265117231403 bayes_pls_golite062009
  • prolactin receptor binding
    		•  2.45721634350294 bayes_pls_golite062009
  • interleukin-12 binding
    		•  1.86853516974406 bayes_pls_golite062009
  • growth hormone activity
    		•  1.51273853550718 bayes_pls_golite062009
  • interleukin-27 binding
    		•  1.47395486119959 bayes_pls_golite062009
  • ciliary neurotrophic factor receptor binding
    		•  1.41876840521933 bayes_pls_golite062009
  • interleukin-6 receptor binding
    		•  1.10578552974983 bayes_pls_golite062009
  • interleukin-2 receptor binding
    		•  0.94093207450743 bayes_pls_golite062009
  • interferon-alpha/beta receptor binding
    		•  0.93290045827216 bayes_pls_golite062009
  • interleukin-12 beta subunit binding
    		•  0.804983553751211 bayes_pls_golite062009
  • hydrolase activity
    		•  0.54680529654691 bayes_pls_golite062009
  • interleukin-4 receptor binding
    		•  0.533617616011661 bayes_pls_golite062009
  • erythropoietin receptor binding
    		•  0.40977611708293 bayes_pls_golite062009
  • catalytic activity
    		•  0.246169290135575 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.010318258615897 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle