YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|1827521, gi|1...
Organism: Homo sapiens
Length: 160 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1827521, gi|1....

Description E-value Query
Range
Subject
Range
IL10_HORSE - Interleukin-10 OS=Equus caballus GN=IL10 PE=2 SV=1
239.0 [0..1] [160..19]
gi|83722853 - gi|83722853|gb|ABC41664.1| interleukin-10 [Oryctolagus cuniculus]
236.0 [0..1] [160..19]
IL10_SAISC - Interleukin-10 OS=Saimiri sciureus GN=IL10 PE=2 SV=1
234.0 [0..1] [160..19]
IL10_CALJA - Interleukin-10 OS=Callithrix jacchus GN=IL10 PE=2 SV=1
232.0 [0..1] [160..19]
IL10_CAVPO - Interleukin-10 OS=Cavia porcellus GN=IL10 PE=3 SV=1
223.0 [0..1] [160..19]
gi|30142086 - gi|30142086|gb|AAP13853.1| interleukin-10 [Peromyscus maniculatus]
221.0 [0..1] [160..19]
IL10_RAT - Interleukin-10 OS=Rattus norvegicus GN=Il10 PE=2 SV=1
219.0 [0..1] [160..19]
IL10_MERUN - Interleukin-10 OS=Meriones unguiculatus GN=IL10 PE=2 SV=1
217.0 [0..1] [160..19]

Back

Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPGQGTQSEN SCTHFPGNLP NMLRDLRDAF SRVKTFFQMK DQLDNLLLKE SLLEDFKGYL  60
   61 GCQALSEMIQ FYLEEVMPQA ENQDPDIKAH VNSLGENLKT LRLRLRRCHR FLPCENKSKA 120
  121 VEQVKNAFNK LQEKGIYKAM SEFDIFINYI EAYMTMKIRN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.30103
Match: 1inrA
Description: CYTOKINE SYNTHESIS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytokine receptor binding 6.47223189691244 bayes_pls_golite062009
cytokine activity 6.38439864086716 bayes_pls_golite062009
receptor binding 5.3304255990112 bayes_pls_golite062009
interleukin-10 receptor binding 4.72567047009114 bayes_pls_golite062009
growth factor activity 4.19013747697608 bayes_pls_golite062009
protein binding 3.26483713001551 bayes_pls_golite062009
hormone activity 2.52921243340076 bayes_pls_golite062009
binding 2.48265117231403 bayes_pls_golite062009
prolactin receptor binding 2.45721634350294 bayes_pls_golite062009
interleukin-12 binding 1.86853516974406 bayes_pls_golite062009
growth hormone activity 1.51273853550718 bayes_pls_golite062009
interleukin-27 binding 1.47395486119959 bayes_pls_golite062009
ciliary neurotrophic factor receptor binding 1.41876840521933 bayes_pls_golite062009
interleukin-6 receptor binding 1.10578552974983 bayes_pls_golite062009
interleukin-2 receptor binding 0.94093207450743 bayes_pls_golite062009
interferon-alpha/beta receptor binding 0.93290045827216 bayes_pls_golite062009
interleukin-12 beta subunit binding 0.804983553751211 bayes_pls_golite062009
hydrolase activity 0.54680529654691 bayes_pls_golite062009
interleukin-4 receptor binding 0.533617616011661 bayes_pls_golite062009
erythropoietin receptor binding 0.40977611708293 bayes_pls_golite062009
catalytic activity 0.246169290135575 bayes_pls_golite062009
transcription regulator activity 0.010318258615897 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle