Protein Overview: PIAS2_RAT

General Information:
Name(s) found:	PIAS2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56404326\|sp\|Q6AZ28.1\|PIAS2_RAT RecName: Full=E3 SUMO-protein ligase PIAS2; AltName: Full=Protein inhibitor of activated STAT2; AltName: Full=Protein inhibitor of activated STAT x; AltName: Full=Msx-interacting-zinc finger protein; AltName: Full=DAB2-in [NCBI NR] gi\|50925461\|gb\|AAH78775.1\| Protein inhibitor of activated STAT, 2 [Rattus norvegicus] [NCBI NR] E3 SUMO-protein ligase PIAS2 OS=Rattus norvegicus GN=Pias2 PE=1 SV=1 [Swiss-Prot] Msx-interacting-zinc finger [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Protein inhibitor of activated STAT2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] E3 SUMO-protein ligase PIAS2 (Protein inhibitor of activated STAT2) (Protein inhibitor of activated STAT x) (Msx-interacting-zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Protein inhibitor of activated STAT 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 MSX-INTERACTING-ZINC FINGER [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting-zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Pias2 E3 SUMO-protein ligase PIAS2 [rat-ipi-250309-contam.fasta] E3 SUMO-protein ligase PIAS2 OS=Rattus norvegicus GN=Pias2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	572 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] nuclear body [UNKNOWN] nuclear speck [IEA]
Biological Process:	response to organic substance [IEP] transcription, DNA-dependent [UNKNOWN] protein sumoylation [UNKNOWN] spermatogenesis [IEP] positive regulation of transcription [IMP] regulation of transcription [IDA] regulation of osteoblast differentiation [UNKNOWN] regulation of androgen receptor signaling pathway [IDA] negative regulation of androgen receptor signaling pathway [UNKNOWN] response to testosterone stimulus [IEP] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] androgen receptor signaling pathway [IMP] positive regulation of dendrite morphogenesis [IMP]
Molecular Function:	nucleic acid binding [IEA] DNA binding [UNKNOWN][IEA] zinc ion binding [IEA] protein binding [UNKNOWN][IPI] RNA polymerase II transcription factor activity [UNKNOWN] androgen receptor binding [IDA][IPI] metal ion binding [IEA] transcription activator activity [UNKNOWN] estrogen receptor binding [IPI] glucocorticoid receptor binding [IPI] SUMO ligase activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADFEELRNM VSSFRVSELQ VLLGFAGRNK SGRKHDLLMR ALHLLKSGCT PAVQIKIREL  60
   61 YRRRYPRTLE GLSDLSTIKS SVFSLDGSSS PVEPDLAVAG IHSLPSTSIA PHSPSSPVAS 120
  121 VLLQDTKPTF EMQQPSPPIP PVHPDVQLKT LPFYDVLDVL IKPTSLVQSS IQRFQEKFFI 180
  181 FALTPQQVRE ICISRDFLPG GRRDYTVQVQ LRLCLAETSC PQEDNYPNSL CIKVNGKLFP 240
  241 LPGYAPPPKN GIEQKRPGRP LNITSLVRLS SAVPNQISIS WASEIGKNYS MSVYLVRQLT 300
  301 SAMLLQRLKM KGIRNPDHSR ALIKEKLTAD PDSEIATTSL RVSLMCPLGK MRLTIPCRAV 360
  361 TCTHLQCFDA ALYLQMNEKK PTWICPVCDK KAAYESLILD GLFMEILNDC SDVDEIKFQE 420
  421 DGSWCPMRPK KEAMKVTSQP CTKVESSSVF SKPCSVTVAS DASKKKIDVI DLTIESSSDE 480
  481 EEDPPAKRKC IFMSETQSSP TKGVLMYQPS SVRVPSVTSV DPAAIPPSLT DYSVPFHHTP 540
  541 VSSMSSDLPG EQRRNDINNE VQLGTSSDTV QQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PIAS2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: