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Protein Overview: SRC_RAT

General Information:
Name(s) found: SRC_RAT [Swiss-Prot]
Description(s) found:
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  • gi|8134704|sp|Q9WUD9.3|SRC_RAT RecName: Full=Proto-oncogene tyrosine-protein kinase Src; AltName: Full=pp60c-src; Short=p60-Src; Short=c-Src [NCBI NR]
  • gi|4574719|gb|AAD24180.1|AF130457_1 tyrosine protein kinase pp60-c-src [Rattus norvegicus] [NCBI NR]
  • Proto-oncogene tyrosine-protein kinase Src OS=Rattus norvegicus GN=Src PE=1 SV=3 [Swiss-Prot]
  • tyrosine protein kinase pp60-c-src [Rattus norvegicus]gi|8134704|sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase SRC (p60-SRC) (C-SRC) [nrdb_11152004_Chlamydomonas]
  • Proto-oncogene tyrosine-protein kinase Src (pp60c-src) (p60-Src) (c-Src) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • tyrosine protein kinase pp60-c-src [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Proto-oncogene tyrosine-protein kinase Src (p60-Src) (c-Src) (pp60c-src) [nr-271106-contam.fasta]
    • Organism: Rattus norvegicus
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: caveola [UNKNOWN]
    cytosol [UNKNOWN]
    plasma membrane [UNKNOWN][IDA]
    Biological Process: cell proliferation [IDA]
    peptidyl-tyrosine phosphorylation [UNKNOWN]
    epidermal growth factor receptor signaling pathway [IEP]
    uterus development [UNKNOWN]
    positive regulation of cell adhesion [IDA]
    protein amino acid phosphorylation [UNKNOWN][IEA]
    branching involved in mammary gland duct morphogenesis [UNKNOWN]
    response to mechanical stimulus [IDA]
    forebrain development [UNKNOWN]
    transcytosis [IDA]
    response to mineralocorticoid stimulus [IDA]
    positive regulation of cytokine secretion [IMP]
    response to fatty acid [IDA]
    positive regulation of smooth muscle cell migration [IMP]
    cell migration [UNKNOWN]
    cell-cell adhesion [IEP]
    positive regulation of insulin receptor signaling pathway [IDA]
    signal transduction [IEA]
    platelet-derived growth factor receptor signaling pathway [IEP]
    Ras protein signal transduction [UNKNOWN]
    response to hydrogen peroxide [IEP]
    response to stress [IDA]
    response to acid [IEP]
    nerve growth factor receptor signaling pathway [IDA]
    positive regulation of glucose metabolic process [IMP]
    oogenesis [UNKNOWN]
    positive regulation of apoptosis [IDA]
    response to interleukin-1 [UNKNOWN]
    regulation of estrogen receptor signaling pathway [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein kinase binding [IPI]
    protein tyrosine kinase activity [UNKNOWN][IDA]
    protein domain specific binding [UNKNOWN]
    protein binding [UNKNOWN][IDA][IPI]
    non-membrane spanning protein tyrosine kinase activity [IEA]
    protein C-terminus binding [IPI]
    protein kinase activity [UNKNOWN]
    transferase activity [IEA]
    SH2 domain binding [UNKNOWN]
    kinase activity [UNKNOWN][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSNKSKPKD ASQRRRSLEP AENVHGAGGA FPASQTPSKP ASADGHRGPN AAFVPPAAAE  60
   61 PKLFGGFNSS DTVTSPQRAG PLAGGVTTFV ALYDYESRTE TDLSFKKGER LQIVNNTEGD 120
  121 WWLAHSLSTG QTGYIPSNYV APFDSIQAEE WYFGKITRRE SERLLLNAEN PRGTFLVRES 180
  181 ETTKGAYCLS VSDFDNAKGL NVKHYKIRKL DSGGFYITSR TQFNSLQQLV AYYSKHADGL 240
  241 CHRLTTVCPT SKPQTQGLAK DAWEIPRESL RLEVKLGQGC FGEVWMGTWN GTTRVAIKTL 300
  301 KPGTMSPEAF LQEAQVMKKL RHEKLVQLYA VVSEEPIYIV TEYMNKGSLL DFLKGETGKY 360
  361 LRLPQLVDMS AQIASGMAYV DRMNYVHRDL RAANILVGEN LVCKVADFGL ARLIEDNEYT 420
  421 ARQGAKFPIK WTAPEAALYG RFTIKSDVWS FGILLTELTT KGRVPYPGMV NREVLDQVER 480
  481 GYRMPCPPEC PESLHDLMCQ CWRKEPEERP TFEYLQAFLE DYFTSTERQY QPGENL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle