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Protein Overview: gi|190408335

General Information:
Name(s) found: gi|190408335 [NCBI NR]
Description(s) found:
  • gi|190408335|gb|EDV11600.1| yeast Ku80 protein [Saccharomyces cerevisiae RM11-1a] [NCBI NR]
    • Organism: Saccharomyces cerevisiae RM11-1a
    Length: 629 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSESTTFIV DVSPSMMKNN NVSKSMAYLE YTLLNKSKKS RKTDWISCYL ANCPVSENSQ  60
   61 EIPNVFQIQS FLAPVTTTAT IGFIKRLKQY CDQHSHDSSN EGLQSMIQCL LVVSLDIKQQ 120
  121 FQARKILKQI VVFTDNLDDL DITDEEIDLL TEELSTRIIL IDCGKDTQEE RKKSNWLKLV 180
  181 EAIPNSRIYN MNELLVEITS PATSVVKPVR VFSGELRLGA DILSTQTSNP SGSMQDENCL 240
  241 CIKVEAFPAT KAVSGLNRKT AVEVEDSQKK ERYVGVKSII EYEIHNEGNK KNVSEDDQSG 300
  301 SSYIPVTISK DSVTKAYRYG ADYVVLPSVL VDQTVYESFP GLDLRGFLNR EALPRYFLTS 360
  361 ESSFITADTR LGCQSDLMAF SALVDVMLEN RKIAVARYVS KKDSEVNMCA LCPVLIEHSN 420
  421 INSEKKFVKS LTLCRLPFAE DERVTDFPKL LDRTTTSGVP LKKETDGHQI DELMEQFVDS 480
  481 MDTDELPEIP LGNYYQPIGE VTTDTTLPLP SLNKDQEENK KDPLRIPTVF VYRQQQVLLE 540
  541 WIHQLMINDS REFEIPELPD SLKNKISPYT HKKFDSTKLV EVLGIKKVDK LKLDSELKTE 600
  601 LEREKIPDLE TLLKRGEQHS RGSPNNSNN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244]
    [269..288]
    [481..513]    		 PSI-BLAST 158.0 DNA binding C-terminal domain of ku70; Ku70 subunit
    2 View Details [245..268]
    [289..445]    		 PSI-BLAST 158.0 DNA binding C-terminal domain of ku70; Ku70 subunit
    3 View Details [446..480]
    [514..629]    		 PSI-BLAST 158.0 DNA binding C-terminal domain of ku70; Ku70 subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • double-stranded telomeric DNA binding
    		•  8.64621483095491 bayes_pls_golite062009
  • DNA-dependent protein kinase activity
    		•  7.33495559751688 bayes_pls_golite062009
  • telomeric DNA binding
    		•  5.16364366157397 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.05720838352689 bayes_pls_golite062009
  • binding
    		•  2.75824485094584 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.08531850924748 bayes_pls_golite062009
  • promoter binding
    		•  1.97164983798318 bayes_pls_golite062009
  • DNA binding
    		•  1.91667917801679 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.69798374416156 bayes_pls_golite062009
  • transcription activator activity
    		•  1.54159704189366 bayes_pls_golite062009
  • protein binding
    		•  1.53311876872122 bayes_pls_golite062009
  • transcription factor activity
    		•  1.37299910766941 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.985753648509262 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.814975395718076 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.720743494912414 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.702777559747981 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.506640285146188 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.45109468643752 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.450760554291027 bayes_pls_golite062009
  • structural molecule activity
    		•  0.375125487765613 bayes_pls_golite062009
  • transporter activity
    		•  0.371057816653329 bayes_pls_golite062009
  • protein complex binding
    		•  0.31789779419928 bayes_pls_golite062009
  • transcription factor binding
    		•  0.184852480703492 bayes_pls_golite062009
  • protein C-terminus binding
    		•  0.15516806759612 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle