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Protein Overview: PNP_STRP1

General Information:
Name(s) found: PNP_STRP1 [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Polyribonucleotide nucleotidyltransferase OS=Streptococcus pyogenes serotype M1 GN=pnp PE=3 SV=1 [Swiss-Prot]
    • Organism: Streptococcus pyogenes serotype M1
    Length: 710 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKQTFTTTF AGKPLVVEVG QVAKQANGAT VVRYGDSTVL TAAVMSKKMA TGDFFPLQVN  60
   61 YEEKMYAAGK FPGGFMKREG RPSTDATLTA RLIDRPIRPM FAEGFRNEVQ VINTVLSYDE 120
  121 NASAPMAAMF GSSLALSISD IPFNGPIAGV QVGYIDGEFI INPDKEQMEA SLLELTVAGS 180
  181 KEAINMVESG AKELSEDIML EALLKGHQAI QELIAFQEQI VAVVGKEKAE VELLQVDVDL 240
  241 QADIVAKYNA QLQKAVQVEE KKAREAATEA VKEMVKAEYE ERYAEDENLA TIMRDVAEIL 300
  301 EQMEHAEVRR LITEDKIRPD GRKIDEIRPL DAVVDFLPKV HGSGLFTRGQ TQALSVLTLA 360
  361 PMGETQIIDG LAPEYKKRFL HHYNFPQYSV GETGRYGAAG RREIGHGALG ERALEQVLPS 420
  421 LEEFPYAIRL VAEVLESNGS SSQASICAGT LALMAGGVPI KAPVAGIAMG LISDGTNYTV 480
  481 LTDIQGLEDH FGDMDFKVAG TREGITALQM DIKIAGITPQ ILEEALAQAK KARFEILDVI 540
  541 EATIAEPRPE LAPTAPKIDT IKIDVDKIKV VIGKGGETID KIIAETGVKI DIDDEGNVSI 600
  601 YSSDQAAIDR TKEIIAGLVR EAKVGEVYHA KVVRIEKFGA FVNLFDKTDA LVHISEIAWT 660
  661 RTTNVSDVLE VGEDVDVKVI KIDEKGRVDA SMKALIPRPP KPEKKEEKHD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..710] PSI-BLAST 150.0 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  3.62650207668685 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.64513435028798 bayes_pls_golite062009
  • exoribonuclease activity
    		•  2.49584565422948 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  2.48625785660839 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.46667410843173 bayes_pls_golite062009
  • RNA binding
    		•  1.96263727771326 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.06121115244578 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.01993495617192 bayes_pls_golite062009
  • binding
    		•  0.953779727473657 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.82905129800799 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.66778558090199 bayes_pls_golite062009
  • structural molecule activity
    		•  0.61730676636766 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.51810239718467 bayes_pls_golite062009
  • DNA binding
    		•  0.42372608430605 bayes_pls_golite062009
    		• 0.416217645025381 bayes_pls_golite062009
  • hydrolase activity
    		•  0.355379071501158 bayes_pls_golite062009
  • catalytic activity
    		•  0.10089766806364 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0287026367466632 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle