Protein Overview: LOX5_RAT

General Information:
Name(s) found:	LOX5_RAT [Swiss-Prot]
Description(s) found: Found 4 descriptions. SHOW ALL	Arachidonate 5-lipoxygenase OS=Rattus norvegicus GN=Alox5 PE=1 SV=3 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	673 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN][IDA][TAS] nucleus [UNKNOWN][IDA] dendrite [IDA] nuclear membrane [UNKNOWN][ISS] soluble fraction [IDA] cytoplasm [UNKNOWN][IEA] sarcolemma [IDA] membrane [IEA] cytosol [UNKNOWN][ISS] nuclear matrix [UNKNOWN][IEA] nuclear envelope lumen [UNKNOWN][ISS]
Biological Process:	inflammatory response [UNKNOWN] leukotriene biosynthetic process [UNKNOWN][TAS] leukotriene metabolic process [UNKNOWN] acute inflammatory response [IMP] lipoxygenase pathway [IMP] positive regulation of vasoconstriction [IMP] sensory perception of pain [IMP] response to nutrient [IEP] oxidation reduction [IEA] leukotriene production involved in inflammatory response [UNKNOWN] arachidonic acid metabolic process [IMP]
Molecular Function:	protein binding [UNKNOWN][IPI][TAS] iron ion binding [IEA] oxidoreductase activity [IEA] metal ion binding [IEA] arachidonate 5-lipoxygenase activity [IMP] lipoxygenase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSYTVTVAT GSQWFAGTDD YIYLSLIGSA GCSEKHLLDK AFYNDFERGG RDSYDVTVDE  60
   61 ELGEIYLVKI EKRKYRLHDD WYLKYITLKT PHDYIEFPCY RWITGEGEIV LRDGCAKLAR 120
  121 DDQIHILKQH RRKELETRQK QYRWMEWNPG FPLSIDAKCH KDLPRDIQFD SEKGVDFVLN 180
  181 YSKAMENLFI NRFMHMFQSS WHDFADFEKI FVKISNTISE RVKNHWQEDL MFGYQFLNGC 240
  241 NPVLIKRCTE LPKKLPVTTE MVECSLERQL SLEQEVQEGN IFIVDYELLD GIDANKTDPC 300
  301 THQFLAAPIC LLYKNLANKI VPIAIQLNQT PGEKNPIFLP TDSKYDWLLA KIWVRSSDFH 360
  361 IHQTITHLLR THLVSEVFGI AMYRQLPAVH PLFKLLVAHV RFTIAINTKA REQLNCEYGL 420
  421 FDKANATGGG GHVQMVQRAV QDLTYSSLCF PEAIKARGMD NTEDIPYYFY RDDGLLVWEA 480
  481 IQSFTTEVVS IYYEDDQVVE EDQELQDFVK DVYVYGMRGR KASGFPKSIK SREKLSEYLT 540
  541 VVIFTASAQH AAVNFGQYDW CSWIPNAPPT MRAPPPTAKG VVTIEQIVDT LPDRGRSCWH 600
  601 LGAVWALSQF QENELFLGMY PEEHFIEKPV KEAMIRFRKN LEAIVSVIAE RNKNKKLPYY 660
  661 YLSPDRIPNS VAI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: LOX5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: