






| Protein: | LBX1_MOUSE |
| Organism: | Mus musculus |
| Length: | 282 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LBX1_MOUSE.
| Description | E-value | Query Range |
Subject Range |
|
|
137.0 | [0..33] | [203..25] |
|
|
132.0 | [0..33] | [257..149] |
|
|
131.0 | [0..1] | [270..1] |
|
|
131.0 | [0..1] | [270..1] |
|
|
130.0 | [0..1] | [270..1] |
|
|
130.0 | [0..1] | [270..1] |
|
|
130.0 | [0..33] | [280..138] |
|
|
129.0 | [0..33] | [257..130] |
|
Region A: Residues: [1-107] |
1 11 21 31 41 51
| | | | | |
1 MTSKEDGKAA PGEERRRSPL DHLPPPANSN KPLTPFSIED ILNKPSVRRS YSLCGAAHLL 60
61 AAADKHAPGG LPLAGRALLS QTSPLCALEE LASKTFKGLE VSVLQAA
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [108-189] |
1 11 21 31 41 51
| | | | | |
1 EGRDGMTIFG QRQTPKKRRK SRTAFTNHQI YELEKRFLYQ KYLSPADRDQ IAQQLGLTNA 60
61 QVITWFQNRR AKLKRDLEEM KA
|
| Detection Method: | |
| Confidence: | 24.69897 |
| Match: | 1pufA |
| Description: | Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.62096064323298 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| protein binding | 0.830419844171551 | bayes_pls_golite062009 |
| serum response element binding | 0.32349914936049 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [190-282] |
1 11 21 31 41 51
| | | | | |
1 DVESAKKLGP SGQMDIVALA ELEQNSEASG GGGGGGCGRA KSRPGSPALP PGAPQAPGGG 60
61 PLQLSPASPL TDQRASSQDC SEDEEDEEID VDD
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.