| Protein: | toy-PA |
| Organism: | Drosophila melanogaster |
| Length: | 543 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for toy-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
282.0 | [0..1] | [316..4] |
|
Region A: Residues: [1-162] |
1 11 21 31 41 51
| | | | | |
1 MMLTTEHIMH GHPHSSVGQS TLFGCSTAGH SGINQLGGVY VNGRPLPDST RQKIVELAHS 60
61 GARPCDISRI LQVSNGCVSK ILGRYYETGS IKPRAIGGSK PRVATTPVVQ KIADYKRECP 120
121 SIFAWEIRDR LLSEQVCNSD NIPSVSSINR VLRNLASQKE QQ
|
| Detection Method: |  |
| Confidence: | 54.522879 |
| Match: | 1k78A |
| Description: | Pax-5 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.5139760613123 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| transcription activator activity | 3.10621734076555 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| protein binding | 1.88087411289001 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [163-271] |
1 11 21 31 41 51
| | | | | |
1 AQQQNESVYE KLRMFNGQTG GWAWYPSNTT TAHLTLPPAA SVVTSPANLS GQADRDDVQK 60
61 RELQFSVEVS HTNSHDSTSD GNSEHNSSGD EDSQMRLRLK RKLQRNRTS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [272-333] |
1 11 21 31 41 51
| | | | | |
1 FSNEQIDSLE KEFERTHYPD VFARERLADK IGLPEARIQV WFSNRRAKWR REEKMRTQRR 60
61 SA
|
| Detection Method: | |
| Confidence: | 11.154902 |
| Match: | 2cueA |
| Description: | Solution structure of the homeobox domain of the human paired box protein Pax-6 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.5139760613123 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| transcription activator activity | 3.10621734076555 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| protein binding | 1.88087411289001 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [334-543] |
1 11 21 31 41 51
| | | | | |
1 DTVDGSGRTS TANNPSGTTA SSSVATSNNS TPGIVNSAIN VAERTSSALV SNSLPEASNG 60
61 PTVLGGEANT THTSSESPPL QPAAPRLPLN SGFNTMYSSI PQPIATMAEN YNSSLGSMTP 120
121 SCLQQRDAYP YMFHDPLSLG SPYVSAHHRN TACNPSAAHQ QPPQHGVYTN SSPMPSSNTG 180
181 VISAGVSVPV QISTQNVSDL TGSNYWPRLQ
|
| Detection Method: | |
| Confidence: | 0.96 |
| Match: | 2j63A |
| Description: | No description for 2j63A was found. |
