| Protein: | Ptx1-PC |
| Organism: | Drosophila melanogaster |
| Length: | 514 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ptx1-PC.
| Description | E-value | Query Range |
Subject Range |
|
|
146.0 | [0..17] | [514..1] |
|
Region A: Residues: [1-136] |
1 11 21 31 41 51
| | | | | |
1 MDRSSAVGGC GGGGGLGVGV VTSSATALGP GGLTNGGGGV VSGALNGLEA MSAESTGLCL 60
61 QDLVSAGTAN GAGSAGSAES ATTTSTALSS GSTGSSTVNG GGSSTSGTEH LHSHHSLHDS 120
121 SSSVSISPAI SSLMPI
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [137-266] |
1 11 21 31 41 51
| | | | | |
1 SSLSHLHHSA GQDLVGGYSQ HPHHTVVPPH TPKHEPLEKL RSLFFSVWAE TGDFRDSHSS 60
61 MTAVANSLDS THLNNFQTSS TSSISNRSRD RKDGNRSVNE TTIKTENISS SGHDEPMTTS 120
121 GEEPKNDKKN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [267-332] |
1 11 21 31 41 51
| | | | | |
1 KRQRRQRTHF TSQQLQELEH TFSRNRYPDM STREEIAMWT NLTEARVRVW FKNRRAKWRK 60
61 RERNAM
|
| Detection Method: | |
| Confidence: | 16.39794 |
| Match: | 1yz8P |
| Description: | Solution structure of the k50 class homeodomain pitx2 bound to dna and implications for mutations that cause rieger syndrome |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.20953772435302 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.26183812259792 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.14886080629275 | bayes_pls_golite062009 |
| chromatin binding | 0.876241359231159 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| protein binding | 0.830419844171551 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.663171909351326 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [333-514] |
1 11 21 31 41 51
| | | | | |
1 NAAVAAADFK SGFGTQFMQP FADDSLYSSY PYNNWTKVPS PLGTKPFPWP VNPLGSMVAG 60
61 NHHQNSVNCF NTGASGVAVS MNNASMLPGS MGSSLSNTSN VGAVGAPCPY TTPANPYMYR 120
121 SAAEPCMSSS MSSSIATLRL KAKQHASAGF GSPYSAPSPV SRSNSAGLSA CQYTGVGVTD 180
181 VV
|
| Detection Method: | |
| Confidence: | 1.22 |
| Match: | 1pk8A |
| Description: | Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP |
Matching Structure (courtesy of the PDB): |
|
