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View Structure Prediction Details

Protein: CG31140-PB
Organism: Drosophila melanogaster
Length: 1055 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31140-PB.

Description E-value Query
Range		 Subject
Range
CG31140-PA - This gene is referred to in FlyBase by the symbol Dmel\CG31140 (CG31140, FBgn0051140). It is a prote...
 924.0 [0..325] [1055..834]

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Predicted Domain #1
Region A:
Residues: [1-224] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADGGHSFVK KTFHKPTYCH HCSDLLWGLI QQGYICEVCN FIIHERCVSS VVTPCSGIAP  60
   61 CIIKNPVAHC WSEPTHHKRK FCTVCRKRLD ETPAVHCLVC EYFAHIECQD FAVPDCTENA 120
  121 TYVPGKELLN VKHQHHWREG NLPSTSKCAY CKKTCWSSEC LTGYRCEWCG MTTHAGCRMY 180
  181 LPTECNFGIL QPIYLPPHSV SIPRTEVPIE AIIGVQVKSK TSLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.39794
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #2
Region A:
Residues: [225-298] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDYSCPRSIS EEFSSGDTPR FKDEESASKA ESGHGPSSGG AGGGGGSGGA GGSSAAGASA  60
   61 SAAGGSSGHY RPDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.59793470114903 bayes_pls_golite062009
nucleic acid binding 0.617293965719078 bayes_pls_golite062009
catalytic activity 0.616333600617445 bayes_pls_golite062009
DNA binding 0.424758271537657 bayes_pls_golite062009
protein binding 0.347976394954253 bayes_pls_golite062009
transcription regulator activity 0.283680459495274 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [299-394] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSGHKSDKSE KDREKKEKER EEKDIEMIKV FDGNNSFRRQ QYRVIIVQRT YTLEQLLTTA  60
   61 LRAFHITRDP QAFYLTDLYA PAGMEDTPML DPTPVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 2coaA
Description: Solution structure of the PH domain of protein kinase C, D2 type from human
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.78130411910911 bayes_pls_golite062009
protein binding 1.46480975291088 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [395-504] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLVHLEGKRP AIYLRFHDRD RGHVRVYPGK LQCSMLEDPY VSVPVDNSTV IKDLIRDALD  60
   61 KFGLQDNQIQ DYRCSEVLLD RGVTERILSW NERPWDIMKQ LGKDSIRQME

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1wxaA
Description: Solution Structure of Ras-binding Domain in Mouse AF-6 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.27715276966235 bayes_pls_golite062009
protein binding 1.21154156832365 bayes_pls_golite062009
kinase activity 0.089926152388164 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0784188873779472 bayes_pls_golite062009
transferase activity 0.0584185769619427 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0414570089711552 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [505-666] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMRFYMQHKQ DPHGPNIALF VGNLPTGLSQ RNYEQILNKY VTDENKFISI GPIYYEYGSV  60
   61 VLTFEDSMKA VRAFYNLRET IIEDKKLLVL LLPNIEPSMV PSDVRPLLVF VNVKSGGCQG 120
  121 LELISSFRKL LNPYQVFDLD NGGPLPGYVQ PITVFVIRPL IF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.08
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.97083555883048 bayes_pls_golite062009
nucleic acid binding 0.682745227966849 bayes_pls_golite062009
protein binding 0.401182256145853 bayes_pls_golite062009
RNA binding 0.0893674167689478 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [667-789] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSIISLYVFR QITNYKILVC GGDGTIGWVL QCLDNVGQDS ECSSPPCAIV PLGTGNDLAR  60
   61 VLCWGSGYTG GEDPLNLLRD VIEAEEIRLD RWTVVFHPED KPEEPAMKAP SQTTGKKKKA 120
  121 HQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.30103
Match: 2jgrA
Description: No description for 2jgrA was found.

Predicted functions:

Term Confidence Notes
kinase activity 1.93010589087203 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.6993468998669 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.62136531467279 bayes_pls_golite062009
transferase activity 1.1287574677626 bayes_pls_golite062009
catalytic activity 0.704900964793432 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [790-1055] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLSQSQQTNQ HHQLPALTSS DISGGAQNED NSQIFVMNNY FGIGIDADLC LDFHNAREEN  60
   61 PNQFNSRLRN KGYYVKMGLR KIVGRKAVKD LQKELRLEVD GKIVELPPVD GIIILNILSW 120
  121 GSGANPWGPD KDDQFSTPNH YDGMLEVVGV TGVVHLGQIQ SGIRTAMRIA QGGHIKIHLN 180
  181 TDMPVQVDGE PWIQSPGDVV VLKSALKATM LKKNKLKMKR RNTEPTMMVA GSAAPPLSLA 240
  241 LPPSVGEVGV AGEGAEGDGG TNNTDF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.04
Match: 2bonA
Description: No description for 2bonA was found.

Predicted functions:

Term Confidence Notes
kinase activity 1.76004122600524 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.55261661837429 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.4762798420527 bayes_pls_golite062009
transferase activity 1.04034215809444 bayes_pls_golite062009
catalytic activity 0.713158176372137 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle