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Protein Overview: CG31140-PB

General Information:
Name(s) found: CG31140-PB / FBpp0083886 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG31140 (CG31140, FBgn0051140). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19788902..19808950. It has the cytological map location 95D1-95D4. Based on sequence similarity, it is predicted to have molecular function</span>: diacylglycerol binding; diacylglycerol kinase activity. It is reported to be involved in the biological process</span>: phosphorylation. 7 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1055 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: intracellular signaling pathway [IEA]
    phosphorylation [NAS]
    activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IEA]
    Molecular Function: diacylglycerol binding [ISS]
    diacylglycerol kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADGGHSFVK KTFHKPTYCH HCSDLLWGLI QQGYICEVCN FIIHERCVSS VVTPCSGIAP  60
   61 CIIKNPVAHC WSEPTHHKRK FCTVCRKRLD ETPAVHCLVC EYFAHIECQD FAVPDCTENA 120
  121 TYVPGKELLN VKHQHHWREG NLPSTSKCAY CKKTCWSSEC LTGYRCEWCG MTTHAGCRMY 180
  181 LPTECNFGIL QPIYLPPHSV SIPRTEVPIE AIIGVQVKSK TSLVRDYSCP RSISEEFSSG 240
  241 DTPRFKDEES ASKAESGHGP SSGGAGGGGG SGGAGGSSAA GASASAAGGS SGHYRPDSGS 300
  301 GHKSDKSEKD REKKEKEREE KDIEMIKVFD GNNSFRRQQY RVIIVQRTYT LEQLLTTALR 360
  361 AFHITRDPQA FYLTDLYAPA GMEDTPMLDP TPVLNLVHLE GKRPAIYLRF HDRDRGHVRV 420
  421 YPGKLQCSML EDPYVSVPVD NSTVIKDLIR DALDKFGLQD NQIQDYRCSE VLLDRGVTER 480
  481 ILSWNERPWD IMKQLGKDSI RQMELMRFYM QHKQDPHGPN IALFVGNLPT GLSQRNYEQI 540
  541 LNKYVTDENK FISIGPIYYE YGSVVLTFED SMKAVRAFYN LRETIIEDKK LLVLLLPNIE 600
  601 PSMVPSDVRP LLVFVNVKSG GCQGLELISS FRKLLNPYQV FDLDNGGPLP GYVQPITVFV 660
  661 IRPLIFDSII SLYVFRQITN YKILVCGGDG TIGWVLQCLD NVGQDSECSS PPCAIVPLGT 720
  721 GNDLARVLCW GSGYTGGEDP LNLLRDVIEA EEIRLDRWTV VFHPEDKPEE PAMKAPSQTT 780
  781 GKKKKAHQAH LSQSQQTNQH HQLPALTSSD ISGGAQNEDN SQIFVMNNYF GIGIDADLCL 840
  841 DFHNAREENP NQFNSRLRNK GYYVKMGLRK IVGRKAVKDL QKELRLEVDG KIVELPPVDG 900
  901 IIILNILSWG SGANPWGPDK DDQFSTPNHY DGMLEVVGVT GVVHLGQIQS GIRTAMRIAQ 960
  961 GGHIKIHLNT DMPVQVDGEP WIQSPGDVVV LKSALKATML KKNKLKMKRR NTEPTMMVAG1020
 1021 SAAPPLSLAL PPSVGEVGVA GEGAEGDGGT NNTDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..224] PSI-BLAST 51.39794 No description for 2i13A was found.
    2 View Details [225..298] PSI-BLAST 15.39794 Five-finger GLI1
    3 View Details [299..394] PSI-BLAST 3.30103 Solution structure of the PH domain of protein kinase C, D2 type from human
    4 View Details [395..504] PSI-BLAST 11.69897 Solution Structure of Ras-binding Domain in Mouse AF-6 Protein
    5 View Details [505..666] FFAS03 1.08 Nuclear ribonucleoprotein A1 (RNP A1, UP1)
    6 View Details [667..789] PSI-BLAST 10.30103 No description for 2jgrA was found.
    7 View Details [790..1055] FFAS03 3.04 No description for 2bonA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.59793470114903 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.617293965719078 bayes_pls_golite062009
  • catalytic activity
    		•  0.616333600617445 bayes_pls_golite062009
  • DNA binding
    		•  0.424758271537657 bayes_pls_golite062009
  • protein binding
    		•  0.347976394954253 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.283680459495274 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  1.78130411910911 bayes_pls_golite062009
  • protein binding
    		•  1.46480975291088 bayes_pls_golite062009
    4
    Term Confidence Notes
  • binding
    		•  1.27715276966235 bayes_pls_golite062009
  • protein binding
    		•  1.21154156832365 bayes_pls_golite062009
  • kinase activity
    		•  0.089926152388164 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0784188873779472 bayes_pls_golite062009
  • transferase activity
    		•  0.0584185769619427 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0414570089711552 bayes_pls_golite062009
    5
    Term Confidence Notes
  • binding
    		•  1.97083555883048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.682745227966849 bayes_pls_golite062009
  • protein binding
    		•  0.401182256145853 bayes_pls_golite062009
  • RNA binding
    		•  0.0893674167689478 bayes_pls_golite062009
    6
    Term Confidence Notes
  • kinase activity
    		•  1.93010589087203 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.6993468998669 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.62136531467279 bayes_pls_golite062009
  • transferase activity
    		•  1.1287574677626 bayes_pls_golite062009
  • catalytic activity
    		•  0.704900964793432 bayes_pls_golite062009
    7
    Term Confidence Notes
  • kinase activity
    		•  1.76004122600524 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.55261661837429 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.4762798420527 bayes_pls_golite062009
  • transferase activity
    		•  1.04034215809444 bayes_pls_golite062009
  • catalytic activity
    		•  0.713158176372137 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle