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Protein Overview: CG31140-PA

General Information:
Name(s) found: CG31140-PA / FBpp0083885 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG31140 (CG31140, FBgn0051140). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19788902..19808950. It has the cytological map location 95D1-95D4. Based on sequence similarity, it is predicted to have molecular function</span>: diacylglycerol binding; diacylglycerol kinase activity. It is reported to be involved in the biological process</span>: phosphorylation. 7 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1564 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: intracellular signaling pathway [IEA]
    phosphorylation [NAS]
    activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IEA]
    Molecular Function: diacylglycerol binding [ISS]
    diacylglycerol kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADGGHSFVK KTFHKPTYCH HCSDLLWGLI QQGYICEVCN FIIHERCVSS VVTPCSGIAP  60
   61 CIIKNPVAHC WSEPTHHKRK FCTVCRKRLD ETPAVHCLVC EYFAHIECQD FAVPDCTENA 120
  121 TYVPGKELLN VKHQHHWREG NLPSTSKCAY CKKTCWSSEC LTGYRCEWCG MTTHAGCRMY 180
  181 LPTECNFGIL QPIYLPPHSV SIPRTEVPIE AIIGVQVKSK TSLVRDYSCP SPDLSCPIPG 240
  241 AGSGSLTSLG LKELLELHRQ RLEQSKQHFL LSTPPTPTSC GSISLCHSPT PSSLTVGETS 300
  301 NEAEQDRERD QDQPEEEPEE ENTEQDSALQ LTTSTSNVIG NLQKWPSANS SLHLLYTNLF 360
  361 RKLGQGKRRR KRGISSGGLS PSEDEDDVDG GVCDISGGDL SDDYDHCDVA LRRRSLRSRQ 420
  421 PRDVSETDYH GDAEAEAEGE TVPRESCYET SDTGGELTNT DDLDSSLNLI SNLSYNSSNN 480
  481 SNACNVPGGA TAPDARNTAT TSTTAPGKSG HALSVQGGRQ QPKTGALAQI KPKPKPILMP 540
  541 KHKAQGKGGS LSSPLSNSNS SDCSSASPSA PATLLQLSPV GRSKSFQESA AITAVSRYKK 600
  601 YGRGLFQRRR SKRSPKNAVG VGGKSNYSLD RLSQNIEITI QDEDGNFHPY DDNYHMLAGR 660
  661 LDATDVDDDV GFDDLYLDDR PSGASDDVAF AGDISDGGAS SRSRASDASD GHVLGRLLRQ 720
  721 VRQGLSVGWR KPRYQKRRAR SISEEFSSGD TPRFKDEESA SKAESGHGPS SGGAGGGGGS 780
  781 GGAGGSSAAG ASASAAGGSS GHYRPDSGSG HKSDKSEKDR EKKEKEREEK DIEMIKVFDG 840
  841 NNSFRRQQYR VIIVQRTYTL EQLLTTALRA FHITRDPQAF YLTDLYAPAG MEDTPMLDPT 900
  901 PVLNLVHLEG KRPAIYLRFH DRDRGHVRVY PGKLQCSMLE DPYVSVPVDN STVIKDLIRD 960
  961 ALDKFGLQDN QIQDYRCSEV LLDRGVTERI LSWNERPWDI MKQLGKDSIR QMELMRFYMQ1020
 1021 HKQDPHGPNI ALFVGNLPTG LSQRNYEQIL NKYVTDENKF ISIGPIYYEY GSVVLTFEDS1080
 1081 MKAVRAFYNL RETIIEDKKL LVLLLPNIEP SMVPSDVRPL LVFVNVKSGG CQGLELISSF1140
 1141 RKLLNPYQVF DLDNGGPLPG YVQPITVFVI RPLIFDSIIS LYVFRQITNY KILVCGGDGT1200
 1201 IGWVLQCLDN VGQDSECSSP PCAIVPLGTG NDLARVLCWG SGYTGGEDPL NLLRDVIEAE1260
 1261 EIRLDRWTVV FHPEDKPEEP AMKAPSQTTG KKKKAHQAHL SQSQQTNQHH QLPALTSSDI1320
 1321 SGGAQNEDNS QIFVMNNYFG IGIDADLCLD FHNAREENPN QFNSRLRNKG YYVKMGLRKI1380
 1381 VGRKAVKDLQ KELRLEVDGK IVELPPVDGI IILNILSWGS GANPWGPDKD DQFSTPNHYD1440
 1441 GMLEVVGVTG VVHLGQIQSG IRTAMRIAQG GHIKIHLNTD MPVQVDGEPW IQSPGDVVVL1500
 1501 KSALKATMLK KNKLKMKRRN TEPTMMVAGS AAPPLSLALP PSVGEVGVAG EGAEGDGGTN1560
 1561 NTDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 8.522879 Crystal Structure of the Human Beta2-Chimaerin
    2 View Details [128..344] PSI-BLAST 53.69897 No description for 2i13A was found.
    3 View Details [345..479] deduced N/A No confident structure predictions are available.
    4 View Details [480..569] deduced N/A No confident structure predictions are available.
    5 View Details [570..809] deduced N/A No confident structure predictions are available.
    6 View Details [810..938] Pfam 14.721246 No description for PF00788.14 was found. No confident structure predictions are available.
    7 View Details [939..1004] PSI-BLAST 4.0 Solution Structure of Ras-binding Domain in Mouse AF-6 Protein
    8 View Details [1005..1176] FFAS03 1.09 Nuclear ribonucleoprotein A1 (RNP A1, UP1)
    9 View Details [1177..1278] PSI-BLAST 6.69897 No description for 2jgrA was found.
    10 View Details [1279..1564] FFAS03 4.16 No description for 2bonA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.28178434527408 bayes_pls_golite062009
  • protein binding
    		•  0.634132597449966 bayes_pls_golite062009
  • catalytic activity
    		•  0.564904183614451 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.509180585718177 bayes_pls_golite062009
  • kinase activity
    		•  0.502413328106933 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.416811228361087 bayes_pls_golite062009
  • transferase activity
    		•  0.255707908488426 bayes_pls_golite062009
  • protein kinase activity
    		•  0.197456871880971 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • binding
    		•  1.27715276966235 bayes_pls_golite062009
  • protein binding
    		•  1.21154156832365 bayes_pls_golite062009
  • kinase activity
    		•  0.089926152388164 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0784188873779472 bayes_pls_golite062009
  • transferase activity
    		•  0.0584185769619427 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0414570089711552 bayes_pls_golite062009
    8
    Term Confidence Notes
  • binding
    		•  1.97083555883048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.682745227966849 bayes_pls_golite062009
  • protein binding
    		•  0.401182256145853 bayes_pls_golite062009
  • RNA binding
    		•  0.0893674167689478 bayes_pls_golite062009
    9 No functions predicted.
    10
    Term Confidence Notes
  • kinase activity
    		•  1.76004122600524 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.55261661837429 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.4762798420527 bayes_pls_golite062009
  • transferase activity
    		•  1.04034215809444 bayes_pls_golite062009
  • catalytic activity
    		•  0.713158176372137 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle