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View Structure Prediction Details

Protein: CG31140-PA
Organism: Drosophila melanogaster
Length: 1564 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31140-PA.

Description E-value Query
Range		 Subject
Range
gi|125775075, gi... - gi|54638530|gb|EAL27932.1| GA16040-PA [Drosophila pseudoobscura], gi|125775075|ref|XP_001358789.1| G...
 1618.0 [0..1] [1564..1]

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Predicted Domain #1
Region A:
Residues: [1-127] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADGGHSFVK KTFHKPTYCH HCSDLLWGLI QQGYICEVCN FIIHERCVSS VVTPCSGIAP  60
   61 CIIKNPVAHC WSEPTHHKRK FCTVCRKRLD ETPAVHCLVC EYFAHIECQD FAVPDCTENA 120
  121 TYVPGKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.28178434527408 bayes_pls_golite062009
protein binding 0.634132597449966 bayes_pls_golite062009
catalytic activity 0.564904183614451 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.509180585718177 bayes_pls_golite062009
kinase activity 0.502413328106933 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.416811228361087 bayes_pls_golite062009
transferase activity 0.255707908488426 bayes_pls_golite062009
protein kinase activity 0.197456871880971 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [128-344] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLNVKHQHHW REGNLPSTSK CAYCKKTCWS SECLTGYRCE WCGMTTHAGC RMYLPTECNF  60
   61 GILQPIYLPP HSVSIPRTEV PIEAIIGVQV KSKTSLVRDY SCPSPDLSCP IPGAGSGSLT 120
  121 SLGLKELLEL HRQRLEQSKQ HFLLSTPPTP TSCGSISLCH SPTPSSLTVG ETSNEAEQDR 180
  181 ERDQDQPEEE PEEENTEQDS ALQLTTSTSN VIGNLQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #3
Region A:
Residues: [345-479] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WPSANSSLHL LYTNLFRKLG QGKRRRKRGI SSGGLSPSED EDDVDGGVCD ISGGDLSDDY  60
   61 DHCDVALRRR SLRSRQPRDV SETDYHGDAE AEAEGETVPR ESCYETSDTG GELTNTDDLD 120
  121 SSLNLISNLS YNSSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [480-569] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSNACNVPGG ATAPDARNTA TTSTTAPGKS GHALSVQGGR QQPKTGALAQ IKPKPKPILM  60
   61 PKHKAQGKGG SLSSPLSNSN SSDCSSASPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [570-809] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APATLLQLSP VGRSKSFQES AAITAVSRYK KYGRGLFQRR RSKRSPKNAV GVGGKSNYSL  60
   61 DRLSQNIEIT IQDEDGNFHP YDDNYHMLAG RLDATDVDDD VGFDDLYLDD RPSGASDDVA 120
  121 FAGDISDGGA SSRSRASDAS DGHVLGRLLR QVRQGLSVGW RKPRYQKRRA RSISEEFSSG 180
  181 DTPRFKDEES ASKAESGHGP SSGGAGGGGG SGGAGGSSAA GASASAAGGS SGHYRPDSGS 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [810-938] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHKSDKSEKD REKKEKEREE KDIEMIKVFD GNNSFRRQQY RVIIVQRTYT LEQLLTTALR  60
   61 AFHITRDPQA FYLTDLYAPA GMEDTPMLDP TPVLNLVHLE GKRPAIYLRF HDRDRGHVRV 120
  121 YPGKLQCSM

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 14.721246
Match: PF00788.14
Description: No description for PF00788.14 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [939-1004] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEDPYVSVPV DNSTVIKDLI RDALDKFGLQ DNQIQDYRCS EVLLDRGVTE RILSWNERPW  60
   61 DIMKQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1wxaA
Description: Solution Structure of Ras-binding Domain in Mouse AF-6 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.27715276966235 bayes_pls_golite062009
protein binding 1.21154156832365 bayes_pls_golite062009
kinase activity 0.089926152388164 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0784188873779472 bayes_pls_golite062009
transferase activity 0.0584185769619427 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0414570089711552 bayes_pls_golite062009

Predicted Domain #8
Region A:
Residues: [1005-1176] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKDSIRQMEL MRFYMQHKQD PHGPNIALFV GNLPTGLSQR NYEQILNKYV TDENKFISIG  60
   61 PIYYEYGSVV LTFEDSMKAV RAFYNLRETI IEDKKLLVLL LPNIEPSMVP SDVRPLLVFV 120
  121 NVKSGGCQGL ELISSFRKLL NPYQVFDLDN GGPLPGYVQP ITVFVIRPLI FD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.09
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.97083555883048 bayes_pls_golite062009
nucleic acid binding 0.682745227966849 bayes_pls_golite062009
protein binding 0.401182256145853 bayes_pls_golite062009
RNA binding 0.0893674167689478 bayes_pls_golite062009

Predicted Domain #9
Region A:
Residues: [1177-1278] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIISLYVFRQ ITNYKILVCG GDGTIGWVLQ CLDNVGQDSE CSSPPCAIVP LGTGNDLARV  60
   61 LCWGSGYTGG EDPLNLLRDV IEAEEIRLDR WTVVFHPEDK PE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 2jgrA
Description: No description for 2jgrA was found.

Predicted Domain #10
Region A:
Residues: [1279-1564] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPAMKAPSQT TGKKKKAHQA HLSQSQQTNQ HHQLPALTSS DISGGAQNED NSQIFVMNNY  60
   61 FGIGIDADLC LDFHNAREEN PNQFNSRLRN KGYYVKMGLR KIVGRKAVKD LQKELRLEVD 120
  121 GKIVELPPVD GIIILNILSW GSGANPWGPD KDDQFSTPNH YDGMLEVVGV TGVVHLGQIQ 180
  181 SGIRTAMRIA QGGHIKIHLN TDMPVQVDGE PWIQSPGDVV VLKSALKATM LKKNKLKMKR 240
  241 RNTEPTMMVA GSAAPPLSLA LPPSVGEVGV AGEGAEGDGG TNNTDF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.16
Match: 2bonA
Description: No description for 2bonA was found.

Predicted functions:

Term Confidence Notes
kinase activity 1.76004122600524 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.55261661837429 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.4762798420527 bayes_pls_golite062009
transferase activity 1.04034215809444 bayes_pls_golite062009
catalytic activity 0.713158176372137 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle