| Protein: | PKD-PB, PKD-PA, ... |
| Organism: | Drosophila melanogaster |
| Length: | 836 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PKD-PB, PKD-PA, ....
| Description | E-value | Query Range |
Subject Range |
|
|
624.0 | [0..5] | [833..48] |
|
Region A: Residues: [1-62] |
1 11 21 31 41 51
| | | | | |
1 MEGPEVTFLF QFGSVRDAVC VPANSLTLKT LKDLACDFIN TKIPDSGLTY LSERILLFVH 60
61 DY
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [63-167] |
1 11 21 31 41 51
| | | | | |
1 STPNVLHIIN SAAEVVDETL VEIVLTASPI LYPTSEMPTL KPHSLNVHSY KGPTFCDFCG 60
61 EMLFGLVRQG LKCDGCGQNY HKRCVVKIPN NCNRSNDATS RRSFT
|
| Detection Method: | |
| Confidence: | 3.01 |
| Match: | 1r79A |
| Description: | Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.28355670417117 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.07238897772131 | bayes_pls_golite062009 |
| kinase activity | 2.00903309297046 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.83466699022067 | bayes_pls_golite062009 |
| protein kinase activity | 1.79721531351546 | bayes_pls_golite062009 |
| signal transducer activity | 1.70194421865269 | bayes_pls_golite062009 |
| molecular transducer activity | 1.70194421865269 | bayes_pls_golite062009 |
| transferase activity | 1.45394179515146 | bayes_pls_golite062009 |
| protein binding | 1.21002143294224 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.12412426198961 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.10707685935826 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.93378879973188 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.717794523788476 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.6091533221871 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.442062495186646 | bayes_pls_golite062009 |
| transcription regulator activity | 0.302160974118897 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.288015740129042 | bayes_pls_golite062009 |
| catalytic activity | 0.216721136299042 | bayes_pls_golite062009 |
|
Region A: Residues: [168-285] |
1 11 21 31 41 51
| | | | | |
1 LQAPRSPSGS SQQSLVSTED STGRNDSSSS LNIPGRHQRT HSSGSRNGLM VLRIPHTFMV 60
61 HTYGIPTVCQ LCKKLLKGLF KQGLQCRDCQ YNTHKKCMDK VPHDCTGEAQ LSQLQIQA
|
| Detection Method: | |
| Confidence: | 18.0 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.36195429973813 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.10625597744594 | bayes_pls_golite062009 |
| kinase activity | 2.03632850156074 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.8531437045627 | bayes_pls_golite062009 |
| protein kinase activity | 1.80739081420522 | bayes_pls_golite062009 |
| signal transducer activity | 1.70650638346167 | bayes_pls_golite062009 |
| molecular transducer activity | 1.70650638346167 | bayes_pls_golite062009 |
| transferase activity | 1.4550521488922 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.39167263636091 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.37139209958305 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.956859696337723 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.911061212692491 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.907368864863833 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.661240850692236 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.53849800215034 | bayes_pls_golite062009 |
| transcription regulator activity | 0.348246993470003 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
|
Region A: Residues: [286-496] |
1 11 21 31 41 51
| | | | | |
1 GAKERDNFFR EEFDDSDGDD GSEYGKYKSA MSSGVNLVAG RPREAPKALT NAHNSPPELV 60
61 NGGLVDDSSV SGGETSKSSS DGQSEQSQSS TSSSPSANIP LMRIVQSVKH TKKRGGQALK 120
121 EGWLVHYTSL DKAVKRYYWR LDSKTITLFV SEQGSKYHKE LPLAELLSIE SHLGDPRPEC 180
181 NYCFELRLPN LSYFVGQDPQ VGAKEEQAVR L
|
| Detection Method: | |
| Confidence: | 4.86 |
| Match: | 1u5eA |
| Description: | Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 3.36168834560682 | bayes_pls_golite062009 |
| actin binding | 3.02207723543271 | bayes_pls_golite062009 |
| binding | 2.73312450062269 | bayes_pls_golite062009 |
| molecular transducer activity | 1.97025592796299 | bayes_pls_golite062009 |
| signal transducer activity | 1.97025592796299 | bayes_pls_golite062009 |
| protein binding | 1.95763087285706 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.71957805451003 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.55414958698765 | bayes_pls_golite062009 |
| protein kinase activity | 1.53914015577029 | bayes_pls_golite062009 |
| kinase activity | 1.52393509273639 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.39413069155432 | bayes_pls_golite062009 |
| actin filament binding | 1.36137023741209 | bayes_pls_golite062009 |
| transferase activity | 1.09391396934652 | bayes_pls_golite062009 |
| receptor activity | 0.931224448280242 | bayes_pls_golite062009 |
| transporter activity | 0.891689255086028 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.830314446783898 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.816556845126609 | bayes_pls_golite062009 |
| chromatin binding | 0.797544081438342 | bayes_pls_golite062009 |
| protein domain specific binding | 0.650240628628722 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.62326150960884 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.487385951045272 | bayes_pls_golite062009 |
| receptor binding | 0.391425518916624 | bayes_pls_golite062009 |
| structural molecule activity | 0.332112521019418 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.328898130778985 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.191468082618045 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.174772802535455 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.0687306550834211 | bayes_pls_golite062009 |
|
Region A: Residues: [497-836] |
1 11 21 31 41 51
| | | | | |
1 PPPDSGIGSD IAKSWETSIR QAFMHVTNTQ CCESEEQVQD MGQLYQIFPD EVLGSGQFGV 60
61 VYGGVHKKTQ REVAIKVIDK LRFPTKQEAQ LKNEVAILQN ISHCGVVNLE RMFETPERIF 120
121 VVMEKLKGDM LEMILSHARG RLSERVTKFL ITQILIALKY LHSQNIVHCD LKPENVLLSS 180
181 DAEFPQVKLC DFGYARIIGE KSFRRSVVGT PAYLAPEVLR NKGYNRSLDM WSVGVIIYVS 240
241 LSGTFPFNEE EDINDQIQNA AFMYPPNPWK EISSNAIDLI NNLLQVKQRK RYTVDKSLLH 300
301 YWLQDKQTYR DLRNLEAQVG AGRYLTHEAD DLRWDCAGDM
|
| Detection Method: | |
| Confidence: | 81.30103 |
| Match: | 2gnfA |
| Description: | No description for 2gnfA was found. |
