| Protein: | CASP2 |
| Organism: | Homo sapiens |
| Length: | 452 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CASP2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..452] | [1..452] |
|
|
0.0 | [1..452] | [1..452] |
|
|
0.0 | [1..452] | [1..452] |
|
|
0.0 | [18..452] | [1..435] |
|
|
0.0 | [23..452] | [10..439] |
|
|
0.0 | [12..452] | [12..452] |
|
Region A: Residues: [1-177] |
1 11 21 31 41 51
| | | | | |
1 MAAPSAGSWS TFQHKELMAA DRGRRILGVC GMHPHHQETL KKNRVVLAKQ LLLSELLEHL 60
61 LEKDIITLEM RELIQAKVGS FSQNVELLNL LPKRGPQAFD AFCEALRETK QGHLEDMLLT 120
121 TLSGLQHVLP PLSCDYDLSL PFPVCESCPL YKKLRLSTDT VEHSLDNKDG PVCLQVK
|
| Detection Method: |  |
| Confidence: | 18.39794 |
| Match: | 1z6tA |
| Description: | Structure of the apoptotic protease-activating factor 1 bound to ADP |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [178-331] |
1 11 21 31 41 51
| | | | | |
1 PCTPEFYQTH FQLAYRLQSR PRGLALVLSN VHFTGEKELE FRSGGDVDHS TLVTLFKLLG 60
61 YDVHVLCDQT AQEMQEKLQN FAQLPAHRVT DSCIVALLSH GVEGAIYGVD GKLLQLQEVF 120
121 QLFDNANCPS LQNKPKMFFI QACRGDETDR GVDQ
|
| Detection Method: | |
| Confidence: | 47.30103 |
| Match: | 1pyoA |
| Description: | Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.24815349282067 | bayes_pls_golite062009 |
| protein binding | 2.96725373477762 | bayes_pls_golite062009 |
| binding | 2.91261616137775 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase regulator activity | 2.60103365510479 | bayes_pls_golite062009 |
| hydrolase activity | 2.45602706385958 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 2.37850336421322 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 2.07426831021634 | bayes_pls_golite062009 |
| apoptotic protease activator activity | 2.001549901512 | bayes_pls_golite062009 |
| cysteine-type endopeptidase activity | 1.82979469421101 | bayes_pls_golite062009 |
| endopeptidase activity | 1.58137850574981 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase inhibitor activity | 1.38256499817012 | bayes_pls_golite062009 |
| catalytic activity | 1.03907950272772 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.0737251792690711 | bayes_pls_golite062009 |
|
Region A: Residues: [332-452] |
1 11 21 31 41 51
| | | | | |
1 QDGKNHAGSP GCEESDAGKE KLPKMRLPTR SDMICGYACL KGTAAMRNTK RGSWYIEALA 60
61 QVFSERACDM HVADMLVKVN ALIKDREGYA PGTEFHRCKE MSEYCSTLCR HLYLFPGHPP 120
121 T
|
| Detection Method: | |
| Confidence: | 27.522879 |
| Match: | 1pyoB |
| Description: | Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho |
| Matching Structure (courtesy of the PDB): |
|
