YRC Public Data Repository - Protein Structure Prediction

Protein:	SYR_LISMO
Organism:	Listeria monocytogenes
Length:	556 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYR_LISMO.

Description	E-value	Query Range	Subject Range
gi\|255519904 - gi\|255519904\|ref\|ZP_05387141.1\| arginyl-tRNA synthetase [Listeria monocytogenes FSL J1-175] gi\|254854387 - gi\|254854387\|ref\|ZP_05243735.1\| arginyl-tRNA synthetase [Listeria monocytogenes FSL R2-503] SYR_LISMF - Arginine--tRNA ligase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=argS PE=3 SV=1 gi\|254880238 - gi\|254880238\|ref\|ZP_05252948.1\| arginyl-tRNA synthetase [Listeria monocytogenes FSL J2-071] gi\|153168709, gi... - gi\|153168709\|ref\|ZP_01928486.1\| arginyl-tRNA synthetase [Listeria monocytogenes FSL N1-017], gi\|1337... gi\|254826340 - gi\|254826340\|ref\|ZP_05231341.1\| arginyl-tRNA synthetase [Listeria monocytogenes FSL J1-194]	384.0	[0..1]	[556..1]
gi\|47018040, gi\|... - gi\|47093569\|ref\|ZP_00231328.1\| arginyl-tRNA synthetase [Listeria monocytogenes str. 4b H7858], gi\|47... SYR_LISMC - Arginine--tRNA ligase OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=argS PE=3 SV=1 SYR_LISMC - Arginyl-tRNA synthetase OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=argS PE=3 SV=1	382.0	[0..1]	[556..1]
SYR_LISIN - Arginine--tRNA ligase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=argS PE=3 SV=1 SYR_LISIN - Arginine--tRNA ligase OS=Listeria innocua GN=argS PE=3 SV=1	380.0	[0..1]	[556..1]
SYR_BACSU - Arginine--tRNA ligase OS=Bacillus subtilis (strain 168) GN=argS PE=3 SV=2 gi\|221325218 - gi\|221325218\|ref\|ZP_03606512.1\| arginyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. SMY] SYR_BACSU - Arginine--tRNA ligase OS=Bacillus subtilis GN=argS PE=3 SV=2 gi\|221316022 - gi\|221316022\|ref\|ZP_03597827.1\| arginyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. NCIB... gi\|221320933 - gi\|221320933\|ref\|ZP_03602227.1\| arginyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. JH64...	364.0	[0..1]	[556..1]
SYR_BACSK - Arginine--tRNA ligase OS=Bacillus clausii (strain KSM-K16) GN=argS PE=3 SV=1	362.0	[0..1]	[556..1]
gi\|89101282, gi\|... - gi\|89101282\|ref\|ZP_01174100.1\| arginyl-tRNA synthetase [Bacillus sp. NRRL B-14911], gi\|89084002\|gb\|E...	361.0	[0..1]	[556..1]
SYR_BACLD - Arginine--tRNA ligase OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 ...	360.0	[0..1]	[556..1]
SYR_OCEIH - Arginine--tRNA ligase OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831... SYR_OCEIH - Arginyl-tRNA synthetase OS=Oceanobacillus iheyensis GN=argS PE=3 SV=1	359.0	[0..1]	[556..1]
SYR_GEOKA - Arginine--tRNA ligase OS=Geobacillus kaustophilus (strain HTA426) GN=argS PE=3 SV=1 SYR_GEOKA - Arginyl-tRNA synthetase OS=Geobacillus kaustophilus GN=argS PE=3 SV=1 gi\|229497829, gi... - gi\|229497829\|ref\|ZP_04391528.1\| arginyl-tRNA synthetase [Geobacillus sp. Y412MC52], gi\|229331255\|gb\|...	358.0	[0..1]	[556..1]
SYR1_BACHD - Arginine--tRNA ligase 1 OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 91... SYR1_BACHD - Arginyl-tRNA synthetase 1 OS=Bacillus halodurans GN=argS1 PE=3 SV=1	357.0	[0..1]	[556..1]

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Predicted Domain #1

Region A:
Residues: [1-556]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVMQENQIK LIEHIKQAVV QAVGLEETEV PEILLEVPKD KKHGDYSTNI AMQLARVAKK  60
   61 APRQIAESIV PELKKDNKLI KEVEIAGPGF INFYLDNAYL TDLVPVILTE DKKYGESDFG 120
  121 KGEKFQIEFV SANPTGDLHL GHARGAAIGD SLANIMKMAG FDVSREYYIN DAGNQINNLV 180
  181 LSAEARYFEA LGLESEFPED GYRGADIISL GKDLAAKYGD KYVHTSEEER RSIFRVDALA 240
  241 FETGKLRADL EEFRVSFDEW FSETSLYEEN KVLPALERLR ENGYIYEQDG ATWLRTTDFE 300
  301 DDKDRVLIKS DGSYTYFLPD IAYHLNKLER GFDVLIDIWG ADHHGYIPRM RAAIEALGYS 360
  361 PNQLEVEIIQ LVHLFEDGVQ VKMSKRTGKS VTMRDLIEEV GLDATRYFFA MRSSDTHMNF 420
  421 DMSLAKSTSN DNPVYYVQYA HARISSILRS GKEQGLEVTK DADMSLLQTE AEYDLLKVLG 480
  481 EFADVVAEAA AKRAPHRIVR YLNDLASAFH RFYNSNKVLD MDNLEVTKAR LALIKTAQIT 540
  541 LRNGLTLLGV SAPEKM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.154902
Match:	1bs2A
Description:	Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
arginine-tRNA ligase activity	5.72854650987135	bayes_pls_golite062009
isoleucine-tRNA ligase activity	3.76808520367507	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
nucleic acid binding	1.03251266786448	bayes_pls_golite062009
binding	0.965037527908742	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
nucleotidyltransferase activity	0.564359271862248	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: