YRC Public Data Repository - Protein Structure Prediction

Protein:	SYR_ECOLI
Organism:	Escherichia coli
Length:	577 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|254793500, gi... - gi\|254793500\|ref\|YP_003078337.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14359], gi... SYR_ECO57 - Arginine--tRNA ligase OS=Escherichia coli O157:H7 GN=argS PE=3 SV=1 gi\|208810380, gi... - gi\|208810380\|ref\|ZP_03252256.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206], gi\|2... gi\|195939580 - gi\|195939580\|ref\|ZP_03084962.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|189376028, gi... - gi\|189376028\|gb\|EDU94444.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC508], gi\|168801... gi\|168789744, gi... - gi\|189370702\|gb\|EDU89118.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC869], gi\|168789... gi\|209767330, gi... - pir\|\|B90952 arginine tRNA synthetase [imported] - Escherichia coli (strain O157:H7, substrain RIMD ... SYR_ECO5E - Arginine--tRNA ligase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=argS PE=3 SV=1 gi\|208818546, gi... - gi\|208818546\|ref\|ZP_03258866.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4042], gi\|2... gi\|13362054, gi\|... - gi\|15831840\|ref\|NP_310613.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|13362... gi\|208731065, gi... - gi\|208816722\|ref\|ZP_03257842.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045], gi\|2... gi\|188017552, gi... - gi\|188017552\|gb\|EDU55674.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4113], gi\|16874... gi\|188999443, gi... - gi\|188999443\|gb\|EDU68429.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi\|16878... gi\|187768070, gi... - gi\|187768070\|gb\|EDU31914.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi\|16877... gi\|189360270, gi... - gi\|189360270\|gb\|EDU78689.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi\|16877... gi\|168757913, gi... - gi\|189355181\|gb\|EDU73600.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4401], gi\|16875...	454.0	[0..1]	[577..1]
SYR_SALTI - Arginyl-tRNA synthetase OS=Salmonella typhi GN=argS PE=3 SV=1 gi\|29141449, gi\|... - gi\|29141449\|ref\|NP_804791.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Ty... gi\|16760859 - gi\|16760859\|ref\|NP_456476.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Ty... SYR_SALTI - Arginine--tRNA ligase OS=Salmonella typhi GN=argS PE=3 SV=1	454.0	[0..1]	[577..1]
gi\|30041576, gi\|... - gi\|30063324\|ref\|NP_837495.1\| arginyl-tRNA synthetase [Shigella flexneri 2a str. 2457T], gi\|30041576\|... gi\|24052255, gi\|... - gi\|24113254\|ref\|NP_707764.1\| arginyl-tRNA synthetase [Shigella flexneri 2a str. 301], gi\|24052255\|gb... SYR_SHIFL - Arginine--tRNA ligase OS=Shigella flexneri GN=argS PE=3 SV=1	454.0	[0..1]	[577..1]
SYR_ECOL6 - Arginine--tRNA ligase OS=Escherichia coli O6 GN=argS PE=3 SV=1 gi\|124498822, gi... - gi\|124531083\|ref\|ZP_01701468.1\| arginyl-tRNA synthetase [Escherichia coli B], gi\|124498822\|gb\|EAY463... gi\|194439027, gi... - gi\|194439027\|ref\|ZP_03071110.1\| arginyl-tRNA synthetase [Escherichia coli 101-1], gi\|194421986\|gb\|ED... gi\|227837269, gi... - gi\|227885696\|ref\|ZP_04003501.1\| arginyl-tRNA synthetase [Escherichia coli 83972], gi\|227837269\|gb\|EE... SYR_ECOSE - Arginine--tRNA ligase OS=Escherichia coli (strain SE11) GN=argS PE=3 SV=1 SYR_ECOLC - Arginine--tRNA ligase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=argS PE=3 SV=1 SYR_ECOL6 - Arginine--tRNA ligase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=argS PE=3 SV...	454.0	[0..1]	[577..1]
SYR_SALPA - Arginine--tRNA ligase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=argS PE=3 SV=1 SYR_SALPA - Arginine--tRNA ligase OS=Salmonella paratyphi A GN=argS PE=3 SV=1 gi\|213426390 - gi\|213426390\|ref\|ZP_03359140.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar... gi\|213163291 - gi\|213163291\|ref\|ZP_03349001.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar... SYR_SALPK - Arginine--tRNA ligase OS=Salmonella paratyphi A (strain AKU_12601) GN=argS PE=3 SV=1	453.0	[0..1]	[577..1]
gi\|167994213, gi... - gi\|205327860\|gb\|EDZ14624.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar 4,[... SYR_SALTS - Arginine--tRNA ligase OS=Salmonella typhimurium (strain SL1344) GN=argS PE=3 SV=1 lcl\|NC_016856.1_... - [gene=argS] [protein=arginyl-tRNA synthetase] [protein_id=YP_005237875.1] [location=2014001..2015734... SYR_SALTY - Arginyl-tRNA synthetase OS=Salmonella typhimurium GN=argS PE=3 SV=2 SYR_SALTY - Arginine--tRNA ligase OS=Salmonella typhimurium GN=argS PE=3 SV=1 SYR_SALTY - Arginine--tRNA ligase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=argS PE=3 S...	453.0	[0..1]	[577..1]
SYR_SHIDS - Arginine--tRNA ligase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=argS PE=3 SV=1	453.0	[0..1]	[577..1]
SYR_SHIBS - Arginine--tRNA ligase OS=Shigella boydii serotype 4 (strain Sb227) GN=argS PE=3 SV=1	453.0	[0..1]	[577..1]
SYR_ECOL5 - Arginine--tRNA ligase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=argS PE=3 SV=1 gi\|191173026, gi... - gi\|191173026\|ref\|ZP_03034560.1\| arginyl-tRNA synthetase [Escherichia coli F11], gi\|190906737\|gb\|EDV6...	452.0	[0..1]	[577..1]
SYR_SALCH - Arginine--tRNA ligase OS=Salmonella choleraesuis (strain SC-B67) GN=argS PE=3 SV=1 SYR_SALCH - Arginyl-tRNA synthetase OS=Salmonella choleraesuis GN=argS PE=3 SV=1 SYR_SALCH - Arginine--tRNA ligase OS=Salmonella choleraesuis GN=argS PE=3 SV=1 SYR_SALHS - Arginine--tRNA ligase OS=Salmonella heidelberg (strain SL476) GN=argS PE=3 SV=1 gi\|205339146, gi... - gi\|205339146\|gb\|EDZ25910.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Hei...	452.0	[0..1]	[577..1]

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Predicted Domain #1

Region A:
Residues: [1-577]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIQALLSEK VRQAMIAAGA PADCEPQVRQ SAKVQFGDYQ ANGMMAVAKK LGMAPRQLAE  60
   61 QVLTHLDLNG IASKVEIAGP GFINIFLDPA FLAEHVQQAL ASDRLGVATP EKQTIVVDYS 120
  121 APNVAKEMHV GHLRSTIIGD AAVRTLEFLG HKVIRANHVG DWGTQFGMLI AWLEKQQQEN 180
  181 AGEMELADLE GFYRDAKKHY DEDEEFAERA RNYVVKLQSG DEYFREMWRK LVDITMTQNQ 240
  241 ITYDRLNVTL TRDDVMGESL YNPMLPGIVA DLKAKGLAVE SEGATVVFLD EFKNKEGEPM 300
  301 GVIIQKKDGG YLYTTTDIAC AKYRYETLHA DRVLYYIDSR QHQHLMQAWA IVRKAGYVPE 360
  361 SVPLEHHMFG MMLGKDGKPF KTRAGGTVKL ADLLDEALER ARRLVAEKNP DMPADELEKL 420
  421 ANAVGIGAVK YADLSKNRTT DYIFDWDNML AFEGNTAPYM QYAYTRVLSV FRKAEIDEEQ 480
  481 LAAAPVIIRE DREAQLAARL LQFEETLTVV AREGTPHVMC AYLYDLAGLF SGFYEHCPIL 540
  541 SAENEEVRNS RLKLAQLTAK TLKLGLDTLG IETVERM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.221849
Match:	1bs2A
Description:	Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
arginine-tRNA ligase activity	5.72854650987135	bayes_pls_golite062009
isoleucine-tRNA ligase activity	3.76808520367507	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
nucleic acid binding	1.03251266786448	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
nucleotidyltransferase activity	0.564359271862248	bayes_pls_golite062009
binding	0.520077014845626	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: