YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|157169762, gi...
Organism:	synthetic construct
Length:	765 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|157169762, gi....

Description	E-value	Query Range	Subject Range
gi\|73949652 - gi\|73949652\|ref\|XP_850350.1\| PREDICTED: similar to zinc transporter ZTL1 isoform 1 isoform 2 [Canis ...	0.0	[1..765]	[1..766]
gi\|37182133 - gi\|37182133\|gb\|AAQ88869.1\| SLC30A5 [Homo sapiens]	0.0	[1..765]	[1..765]
gi\|109077463 - gi\|109077463\|ref\|XP_001090696.1\| PREDICTED: similar to zinc transporter ZTL1 isoform 1 isoform 2 [Ma...	0.0	[1..765]	[1..766]
gi\|114599923 - gi\|114599923\|ref\|XP_001161060.1\| PREDICTED: zinc transporter ZTL1 isoform 5 [Pan troglodytes]	0.0	[1..765]	[1..765]
gi\|62642842, gi\|... - gi\|62642842\|ref\|XP_226722.3\| PREDICTED: similar to solute carrier family 30 (zinc transporter), memb...	0.0	[22..765]	[20..760]
ZNT5_MOUSE - Zinc transporter 5 OS=Mus musculus GN=Slc30a5 PE=1 SV=1	0.0	[1..765]	[1..761]
gi\|76646229 - gi\|76646229\|ref\|XP_584911.2\| PREDICTED: similar to zinc transporter ZTL1 isoform 1 [Bos taurus]	0.0	[1..765]	[1..769]

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Predicted Domain #1

Region A:
Residues: [1-100]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKYGGDVL AGPGGGGGLG PVDVPSARLT KYIVLLCFTK FLKAVGLFES YDLLKAVHIV  60
   61 QFIFILKLGT AFFMVLFQKP FSSGKTITKH QWIKIFKHAV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [101-170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGCIISLLWF FGLTLCGPLR TLLLFEHSDI VVISLLSVLF TSSGGGPAKT RGAAFFIIAV  60
   61 ICLLLFDNDD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [171-393]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMAKMAEHPE GHHDSALTHM LYTAIAFLGV ADHKGGVLLL VLALCCKVGF HTASRKLSVD  60
   61 VGGAKRLQAL SHLVSVLLLC PWVIVLSVTT ESKVESWFSL IMPFATVIFF VMILDFYVDS 120
  121 ICSVKMEVSK CARYGSFPIF ISALLFGNFW THPITDQLRA MNKAAHQEST EHVLSGGVVV 180
  181 SAIFFILSAN ILSSPSKRGQ KGTLIGYSPE GTPLYNFMGD AFQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [394-765]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSSQSIPRFI KESLKQILEE SDSRQIFYFL CLNLLFTFVE LFYGVLTNSL GLISDGFHML  60
   61 FDCSALVMGL FAALMSRWKA TRIFSYGYGR IEILSGFING LFLIVIAFFV FMESVARLID 120
  121 PPELDTHMLT PVSVGGLIVN LIGICAFSHA HSHAHGASQG SCHSSDHSHS HHMHGHSDHG 180
  181 HGHSHGSAGG GMNANMRGVF LHVLADTLGS IGVIVSTVLI EQFGWFIADP LCSLFIAILI 240
  241 FLSVVPLIKD ACQVLLLRLP PEYEKELHIA LEKIQKIEGL ISYRDPHFWR HSASIVAGTI 300
  301 HIQVTSDVLE QRIVQQVTGI LKDAGVNNLT IQVEKEAYFQ HMSGLSTGFH DVLAMTKQME 360
  361 SMKYCKDGTY IM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.69897
Match:	2qfiA
Description:	No description for 2qfiA was found.

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	6.60087208506814	bayes_pls_golite062009
ion transmembrane transporter activity	6.49419690808578	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	6.066906606566	bayes_pls_golite062009
transporter activity	4.27173462293249	bayes_pls_golite062009
substrate-specific transporter activity	4.19993137135137	bayes_pls_golite062009
transmembrane transporter activity	4.18558383943492	bayes_pls_golite062009
metal ion transmembrane transporter activity	3.30217266286364	bayes_pls_golite062009
efflux transmembrane transporter activity	2.65640147236	bayes_pls_golite062009
cation channel activity	2.58631873778428	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.32644140472297	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.19343183150052	bayes_pls_golite062009
ion channel activity	2.03125515494926	bayes_pls_golite062009
substrate-specific channel activity	1.95530036989194	bayes_pls_golite062009
passive transmembrane transporter activity	1.95111816239105	bayes_pls_golite062009
channel activity	1.95111816239105	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.31663166812163	bayes_pls_golite062009
binding	1.27456652114636	bayes_pls_golite062009
cadmium ion transmembrane transporter activity	0.661906409169955	bayes_pls_golite062009
active transmembrane transporter activity	0.490905558612378	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.376948884172728	bayes_pls_golite062009
protein binding	0.311357063667067	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: