YRC Public Data Repository - Protein Structure Prediction

Protein:	FOCA_ECOLI
Organism:	Escherichia coli
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FOCA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|227838883, gi... - gi\|227884131\|ref\|ZP_04001936.1\| formate transporter [Escherichia coli 83972], gi\|227838883\|gb\|EEJ493... gi\|117623122, gi... - gi\|117623122\|ref\|YP_852035.1\| formate transporter [Escherichia coli APEC O1], gi\|115512246\|gb\|ABJ003... gi\|226898318, gi... - gi\|237707108\|ref\|ZP_04537589.1\| formate transporter [Escherichia sp. 3_2_53FAA], gi\|226898318\|gb\|EEH... gi\|26246929, gi\|... - gi\|26246929\|ref\|NP_752969.1\| formate transporter [Escherichia coli CFT073], gi\|26107329\|gb\|AAN79512.... gi\|110641101, gi... - gi\|110641101\|ref\|YP_668831.1\| formate transporter [Escherichia coli 536], gi\|110342693\|gb\|ABG68930.1... gi\|91071579, gi\|... - gi\|91210005\|ref\|YP_539991.1\| formate transporter [Escherichia coli UTI89], gi\|91071579\|gb\|ABE06460.1...	309.0	[0..1]	[285..114]
gi\|110614460, gi... - gi\|110804912\|ref\|YP_688432.1\| formate transporter [Shigella flexneri 5 str. 8401], gi\|110614460\|gb\|A... gi\|24112312, gi\|... - ref\|NP_706822.1\| probable formate transporter (formate channel 1) [Shigella flexneri 2a str. 301], ...	304.0	[0..1]	[285..59]
gi\|62127131, gi\|... - gi\|62179498\|ref\|YP_215915.1\| formate transporter [Salmonella enterica subsp. enterica serovar Choler...	300.0	[0..1]	[285..41]
gi\|82719699, gi\|... - gi\|82742945\|ref\|ZP_00905618.1\| Formate/nitrite transporter [Shewanella sp. W3-18-1], gi\|82719699\|gb\|... gi\|146293472, gi... - gi\|77815016\|ref\|ZP_00814261.1\| Formate/nitrite transporter [Shewanella putrefaciens CN-32], gi\|77809...	298.0	[0..13]	[284..35]
gi\|90310014, gi\|... - gi\|90408875\|ref\|ZP_01217014.1\| putative formate transporter 1 [Psychromonas sp. CNPT3], gi\|90310014\|...	296.0	[0..15]	[284..1]
gi\|238789325, gi... - gi\|77974841\|ref\|ZP_00830379.1\| COG2116: Formate/nitrite family of transporters [Yersinia frederiksen...	296.0	[0..1]	[285..1]
gi\|238720308, gi... - gi\|77963087\|ref\|ZP_00826900.1\| COG2116: Formate/nitrite family of transporters [Yersinia mollaretii ...	294.0	[0..1]	[285..1]
gi\|238792406, gi... - gi\|77979241\|ref\|ZP_00834661.1\| COG2116: Formate/nitrite family of transporters [Yersinia intermedia ...	294.0	[0..1]	[285..1]
gi\|238714586, gi... - gi\|77958324\|ref\|ZP_00822359.1\| COG2116: Formate/nitrite family of transporters [Yersinia bercovieri ...	293.0	[0..1]	[285..1]
gi\|89072731, gi\|... - gi\|89072731\|ref\|ZP_01159296.1\| putative FNT family, formate transporter (formate channel 1) [Photoba...	293.0	[0..3]	[280..2]

Back

Predicted Domain #1

Region A:
Residues: [1-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKADNPFDLL LPAAMAKVAE EAGVYKATKH PLKTFYLAIT AGVFISIAFV FYITATTGTG  60
   61 TMPFGMAKLV GGICFSLGLI LCVVCGADLF TSTVLIVVAK ASGRITWGQL AKNWLNVYFG 120
  121 NLVGALLFVL LMWLSGEYMT ANGQWGLNVL QTADHKVHHT FIEAVCLGIL ANLMVCLAVW 180
  181 MSYSGRSLMD KAFIMVLPVA MFVASGFEHS IANMFMIPMG IVIRDFASPE FWTAVGSAPE 240
  241 NFSHLTVMNF ITDNLIPVTI GNIIGGGLLV GLTYWVIYLR ENDHH

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.49
Match:	1fx8A
Description:	Glycerol uptake facilitator protein GlpF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	3.29716739878922	bayes_pls_golite062009
substrate-specific channel activity	2.94662039655367	bayes_pls_golite062009
channel activity	2.9414344431192	bayes_pls_golite062009
passive transmembrane transporter activity	2.9414344431192	bayes_pls_golite062009
transmembrane transporter activity	2.89191055188639	bayes_pls_golite062009
substrate-specific transporter activity	2.82037090563528	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.65037422078415	bayes_pls_golite062009
nitrate transmembrane transporter activity	1.47913191081789	bayes_pls_golite062009
water transmembrane transporter activity	1.45822447350992	bayes_pls_golite062009
water channel activity	1.30496704143853	bayes_pls_golite062009
anion transmembrane transporter activity	0.909897861102259	bayes_pls_golite062009
ion transmembrane transporter activity	0.843641784538908	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	0.665829718813242	bayes_pls_golite062009
organic acid transmembrane transporter activity	0.641796590324282	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	0.619845435332912	bayes_pls_golite062009
amine transmembrane transporter activity	0.232492592199022	bayes_pls_golite062009
cation transmembrane transporter activity	0.156116095173723	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: