YRC Public Data Repository - Protein Structure Prediction

Protein:	FEOB_ECOLI
Organism:	Escherichia coli
Length:	773 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FEOB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|82778774, gi\|... - gi\|82778774\|ref\|YP_405123.1\| ferrous iron transport protein B [Shigella dysenteriae Sd197], gi\|81242...	718.0	[0..1]	[773..1]
gi\|191171509, gi... - gi\|75241500\|ref\|ZP_00725345.1\| COG0370: Fe2+ transport system protein B [Escherichia coli F11], gi\|1... gi\|110345234, gi... - gi\|110643642\|ref\|YP_671372.1\| ferrous iron transport protein B [Escherichia coli 536], gi\|110345234\|...	718.0	[0..1]	[773..1]
gi\|75516123, gi\|... - gi\|75516123\|ref\|ZP_00738241.1\| COG0370: Fe2+ transport system protein B [Escherichia coli 53638], gi... gi\|193061899, gi... - gi\|75260302\|ref\|ZP_00731570.1\| COG0370: Fe2+ transport system protein B [Escherichia coli E22], gi\|1... gi\|75211775, gi\|... - gi\|75211775\|ref\|ZP_00711839.1\| COG0370: Fe2+ transport system protein B [Escherichia coli B171], gi\|... gi\|75197340, gi\|... - gi\|75197340\|ref\|ZP_00707410.1\| COG0370: Fe2+ transport system protein B [Escherichia coli HS], gi\|15... gi\|209397247, gi... - gi\|209397247\|ref\|YP_002272845.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4... gi\|209914125, gi... - gi\|209920866\|ref\|YP_002294950.1\| ferrous iron transport protein B [Escherichia coli SE11], gi\|209914... gi\|217320720, gi... - gi\|217324499\|ref\|ZP_03440583.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. TW14... gi\|75188183, gi\|... - gi\|75188183\|ref\|ZP_00701450.1\| COG0370: Fe2+ transport system protein B [Escherichia coli E24377A], ... FEOB_ECO57 - Ferrous iron transport protein B OS=Escherichia coli O157:H7 GN=feoB PE=3 SV=1 gi\|124528182, gi... - gi\|124528182\|ref\|ZP_01699515.1\| ferrous iron transport protein B [Escherichia coli B], gi\|124500837\|... gi\|168779493, gi... - gi\|189002363\|gb\|EDU71349.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4076],... gi\|254594724, gi... - gi\|254795324\|ref\|YP_003080161.1\| fused ferrous iron transporter, protein B: GTP-binding protein and ... gi\|189374492, gi... - gi\|189374492\|gb\|EDU92908.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC869], ... gi\|189380165, gi... - gi\|189380165\|gb\|EDU98581.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC508], ... gi\|169753283, gi... - gi\|170018355\|ref\|YP_001723309.1\| ferrous iron transport protein B [Escherichia coli ATCC 8739], gi\|1... gi\|195934898 - gi\|195934898\|ref\|ZP_03080280.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC40... gi\|208807832, gi... - gi\|208807832\|ref\|ZP_03250169.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC42... gi\|208812284, gi... - gi\|208812284\|ref\|ZP_03253613.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC40... gi\|208818539, gi... - gi\|208818539\|ref\|ZP_03258859.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC40... gi\|12518039, gi\|... - gi\|15803913\|ref\|NP_289949.1\| ferrous iron transport protein B [Escherichia coli O157:H7 EDL933], gi\|... gi\|209756480, gi... - pir\|\|B86006 ferrous iron transport protein B [imported] - Escherichia coli (strain O157:H7, substrai... gi\|168747113, gi... - gi\|188018362\|gb\|EDU56484.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4113],... gi\|189359299, gi... - gi\|189359299\|gb\|EDU77718.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4401],... gi\|168759434, gi... - gi\|189369813\|gb\|EDU88229.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4501],... gi\|168765757, gi... - gi\|189364596\|gb\|EDU83015.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4486],... gi\|168772699, gi... - gi\|187771577\|gb\|EDU35421.1\| ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4196],...	718.0	[0..1]	[773..1]
FEOB_ECOL6 - Ferrous iron transport protein B OS=Escherichia coli O6 GN=feoB PE=2 SV=2 gi\|227839422, gi... - gi\|227883543\|ref\|ZP_04001348.1\| FeoB family ferrous iron (Fe2+) uptake protein [Escherichia coli 839... FEOB_ECOL6 - Ferrous iron transport protein B OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=f...	718.0	[0..1]	[773..1]
gi\|170682365, gi... - gi\|170682365\|ref\|YP_001745657.1\| ferrous iron transport protein B [Escherichia coli SMS-3-5], gi\|170... gi\|218697092, gi... - gi\|218697092\|ref\|YP_002404759.1\| ferrous iron transport protein B [Escherichia coli 55989], gi\|21835... gi\|193068858, gi... - gi\|75237010\|ref\|ZP_00721066.1\| COG0370: Fe2+ transport system protein B [Escherichia coli E110019], ... gi\|191167889, gi... - gi\|75228936\|ref\|ZP_00715528.1\| COG0370: Fe2+ transport system protein B [Escherichia coli B7A], gi\|1... gi\|187732140, gi... - gi\|75179972\|ref\|ZP_00699959.1\| COG0370: Fe2+ transport system protein B [Shigella boydii BS512], gi\|... gi\|194425334, gi... - gi\|83588726\|ref\|ZP_00927350.1\| COG0370: Fe2+ transport system protein B [Escherichia coli 101-1], gi... gi\|251786659, gi... - gi\|251786659\|ref\|YP_003000963.1\| hypothetical protein B21_03213 [Escherichia coli BL21], gi\|24237893... gi\|253979394, gi... - gi\|254290087\|ref\|YP_003055835.1\| ferrous iron transport protein B [Escherichia coli BL21(DE3)], gi\|2... gi\|253975238, gi... - gi\|254163337\|ref\|YP_003046445.1\| ferrous iron transport protein B [Escherichia coli B str. REL606], ...	717.0	[0..1]	[773..1]
gi\|226902404, gi... - gi\|237703140\|ref\|ZP_04533621.1\| ferrous iron transporter B [Escherichia sp. 3_2_53FAA], gi\|226902404... gi\|91074458, gi\|... - gi\|91212884\|ref\|YP_542870.1\| ferrous iron transport protein B [Escherichia coli UTI89], gi\|91074458\|... gi\|115514799, gi... - gi\|117625675\|ref\|YP_858998.1\| ferrous iron transport protein B [Escherichia coli APEC O1], gi\|115514...	717.0	[0..1]	[773..5]
gi\|110807241, gi... - gi\|110807241\|ref\|YP_690761.1\| ferrous iron transport protein B [Shigella flexneri 5 str. 8401], gi\|1...	717.0	[0..1]	[773..1]
gi\|26110439, gi\|... - gi\|26250010\|ref\|NP_756050.1\| Ferrous iron transport protein B [Escherichia coli CFT073], gi\|26110439...	716.0	[0..1]	[773..5]
gi\|74313912, gi\|... - gi\|74313912\|ref\|YP_312331.1\| ferrous iron transport protein B [Shigella sonnei Ss046], gi\|73857389\|g...	716.0	[0..1]	[773..1]
gi\|81247177, gi\|... - gi\|82545766\|ref\|YP_409713.1\| ferrous iron transport protein B [Shigella boydii Sb227], gi\|81247177\|g...	716.0	[0..1]	[773..1]

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Predicted Domain #1

Region A:
Residues: [1-357]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKLTIGLIG NPNSGKTTLF NQLTGSRQRV GNWAGVTVER KEGQFSTTDH QVTLVDLPGT  60
   61 YSLTTISSQT SLDEQIACHY ILSGDADLLI NVVDASNLER NLYLTLQLLE LGIPCIVALN 120
  121 MLDIAEKQNI RIEIDALSAR LGCPVIPLVS TRGRGIEALK LAIDRYKANE NVELVHYAQP 180
  181 LLNEADSLAK VMPSDIPLKQ RRWLGLQMLE GDIYSRAYAG EASQHLDAAL ARLRNEMDDP 240
  241 ALHIADARYQ CIAAICDVVS NTLTAEPSRF TTAVDKIVLN RFLGLPIFLF VMYLMFLLAI 300
  301 NIGGALQPLF DVGSVALFVH GIQWIGYTLH FPDWLTIFLA QGLGGGINTV LPLVPQI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.221849
Match:	1b23P
Description:	Elongation factor Tu (EF-Tu), domain 2; Elongation factor Tu (EF-Tu); Elongation factor Tu (EF-Tu), N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphatase activity	1.95073642969863	bayes_pls_golite062009
pyrophosphatase activity	1.91141407779641	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.9017593265179	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.90014393273511	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.608578860823	bayes_pls_golite062009
transporter activity	1.55572428045529	bayes_pls_golite062009
ATPase activity	1.48474288797022	bayes_pls_golite062009
transmembrane transporter activity	1.38483976298883	bayes_pls_golite062009
ATPase activity, coupled	1.37457738689583	bayes_pls_golite062009
ion transmembrane transporter activity	1.32358677895008	bayes_pls_golite062009
active transmembrane transporter activity	1.24278046928678	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.2014318795788	bayes_pls_golite062009
primary active transmembrane transporter activity	1.19670408144267	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	1.17063957238561	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	1.16918853509059	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	1.16885789920943	bayes_pls_golite062009
hydrolase activity	1.09839981963412	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	1.05321289029555	bayes_pls_golite062009
cation transmembrane transporter activity	1.01376912193868	bayes_pls_golite062009
binding	0.855534295206446	bayes_pls_golite062009
catalytic activity	0.605053499033488	bayes_pls_golite062009
purine ribonucleotide binding	0.5127850474754	bayes_pls_golite062009
ribonucleotide binding	0.51230334374838	bayes_pls_golite062009
purine nucleotide binding	0.50688037036449	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.499229734997878	bayes_pls_golite062009
nucleotide binding	0.49473184426584	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.462652239329679	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.338494663195175	bayes_pls_golite062009
substrate-specific transporter activity	0.0838665746103899	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [358-447]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMMYLFLSFL EDSGYMARAA FVMDRLMQAL GLPGKSFVPL IVGFGCNVPS VMGARTLDAP  60
   61 RERLMTIMMA PFMSCGARLA IFAVFAAAFF

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	10.443697
Match:	PF07670.5
Description:	No description for PF07670.5 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [448-494]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQNGALAVFS LYMLGIVMAV LTGLMLKYTI MRGEATPFVM ELPVYHV

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	21.769551
Match:	PF07664.3
Description:	No description for PF07664.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [495-687]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHVKSLIIQT WQRLKGFVLR AGKVIIIVSI FLSAFNSFSL SGKIVDNIND SALASVSRVI  60
   61 TPVFKPIGVH EDNWQATVGL FTGAMAKEVV VGTLNTLYTA ENIQDEEFNP AEFNLGEELF 120
  121 SAIDETWQSL KDTFSLSVLM NPIEASKGDG EMGTGAMGVM DQKFGSAAAA YSYLIFVLLY 180
  181 VPCISVMGAI ARE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	16.455932
Match:	PF07670.5
Description:	No description for PF07670.5 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [688-773]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSRGWMGFSI LWGLNIAYSL ATLFYQVASY SQHPTYSLVC ILAVILFNIV VIGLLRRARS  60
   61 RVDIELLATR KSVSSCCAAS TTGDCH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: