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View Structure Prediction Details

Protein: DHAS_ECOLI
Organism: Escherichia coli
Length: 367 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DHAS_ECOLI.

Description E-value Query
Range		 Subject
Range
gi|62318276 - gi|62318276|dbj|BAD93764.1| Glyceraldehyde-3-phosphate dehydrogenase [Meriones unguiculatus]
 325.0 [0..1] [367..1]
gi|74194852 - gi|74194852|dbj|BAE26016.1| unnamed protein product [Mus musculus]
 325.0 [0..1] [367..1]
G3P_CRIGR - Glyceraldehyde-3-phosphate dehydrogenase OS=Cricetulus griseus GN=GAPDH PE=2 SV=2
 324.0 [0..1] [367..1]
G3P_RAT - Glyceraldehyde-3-phosphate dehydrogenase OS=Rattus norvegicus GN=Gapdh PE=1 SV=3
 324.0 [0..1] [367..1]
DHAS_AQUAE - Aspartate-semialdehyde dehydrogenase OS=Aquifex aeolicus GN=asd PE=3 SV=1
DHAS_AQUAE - Aspartate-semialdehyde dehydrogenase OS=Aquifex aeolicus (strain VF5) GN=asd PE=3 SV=1
 323.0 [0..2] [366..3]

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Predicted Domain #1
Region A:
Residues: [1-367] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNVGFIGWR GMVGSVLMQR MVEERDFDAI RPVFFSTSQL GQAAPSFGGT TGTLQDAFDL  60
   61 EALKALDIIV TCQGGDYTNE IYPKLRESGW QGYWIDAASS LRMKDDAIII LDPVNQDVIT 120
  121 DGLNNGIRTF VGGNCTVSLM LMSLGGLFAN DLVDWVSVAT YQAASGGGAR HMRELLTQMG 180
  181 HLYGHVADEL ATPSSAILDI ERKVTTLTRS GELPVDNFGV PLAGSLIPWI DKQLDNGQSR 240
  241 EEWKGQAETN KILNTSSVIP VDGLCVRVGA LRCHSQAFTI KLKKDVSIPT VEELLAAHNP 300
  301 WAKVVPNDRE ITMRELTPAA VTGTLTTPVG RLRKLNMGPE FLSAFTVGDQ LLWGAAEPLR 360
  361 RMLRQLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.39794
Match: 1brmA
Description: Aspartate beta-semialdehyde dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartate-semialdehyde dehydrogenase activity 3.92511214237139 bayes_pls_golite062009
catalytic activity 2.91887313269429 bayes_pls_golite062009
oxidoreductase activity 2.86254373278283 bayes_pls_golite062009
dihydrodipicolinate reductase activity 2.74085594134831 bayes_pls_golite062009
fatty acid synthase activity 1.2948167480504 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 1.19591951564949 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1.07932840802619 bayes_pls_golite062009
phosphoglycerate dehydrogenase activity 0.815013397873281 bayes_pls_golite062009
ketol-acid reductoisomerase activity 0.57325534211306 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.43885070515079 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.23458869447046 bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity 0.22364954992375 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.22262673350502 bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase activity 0.0876163188309598 bayes_pls_golite062009
saccharopine dehydrogenase activity 0.0126684068691896 bayes_pls_golite062009
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