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Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ketol-acid reductoisomerase activity
Acc: GO:0004455
Aspect: Molecular Function
Desc: Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
Synonyms:
  • dihydroxyisovalerate dehydrogenase (isomerizing) activity
  • acetohydroxy acid isomeroreductase activity
  • dihydroxyisovalerate (isomerizing) dehydrogenase activity
  • ketol acid reductoisomerase activity
  • reductoisomerase activity
  • 2-hydroxy-3-keto acid reductoisomerase activity
  • isomeroreductase activity
  • acetohydroxy acid reductoisomerase activity
  • alpha-keto-beta-hydroxylacyl reductoisomerase activity
  • (R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
  • acetolactate reductoisomerase activity
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004455 - ketol-acid reductoisomerase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle