YRC Public Data Repository - Protein Structure Prediction

Protein:	DEOR_ECOLI
Organism:	Escherichia coli
Length:	252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEOR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|77978684, gi\|... - gi\|77978684\|ref\|ZP_00834110.1\| COG1349: Transcriptional regulators of sugar metabolism [Yersinia int...	233.0	[0..3]	[250..1]
gi\|91191480, gi\|... - gi\|91223394\|ref\|ZP_01258659.1\| transcriptional regulator, DeoR family protein [Vibrio alginolyticus ...	232.0	[0..3]	[250..1]
gi\|254229357, gi... - gi\|75855918\|ref\|ZP_00763557.1\| COG1349: Transcriptional regulators of sugar metabolism [Vibrio sp. E...	232.0	[0..3]	[250..1]
gi\|37199558, gi\|... - gi\|37680809\|ref\|NP_935418.1\| transcriptional regulator of sugar metabolism [Vibrio vulnificus YJ016]...	232.0	[0..2]	[251..9]
gi\|89074567, gi\|... - gi\|89074567\|ref\|ZP_01161039.1\| transcriptional regulator, DeoR family protein [Photobacterium sp. SK...	231.0	[0..3]	[250..1]
gi\|115514811, gi... - gi\|117625687\|ref\|YP_859010.1\| DNA-binding transcriptional repressor GlpR [Escherichia coli APEC O1],...	231.0	[0..1]	[250..11]
gi\|255054070, gi... - gi\|255054070\|ref\|ZP_05306318.1\| transcriptional regulator, DeoR family [Pectobacterium wasabiae WPP1... gi\|253690290, gi... - gi\|253690290\|ref\|YP_003019480.1\| transcriptional regulator, DeoR family [Pectobacterium carotovorum ... gi\|50123057, gi\|... - gi\|50123057\|ref\|YP_052224.1\| DNA-binding transcriptional repressor GlpR [Pectobacterium atrosepticum...	231.0	[0..3]	[250..1]
gi\|83571653 - gi\|83571653\|ref\|ZP_00923093.1\| COG1349: Transcriptional regulators of sugar metabolism [Shigella dys...	230.0	[0..1]	[250..11]
gi\|75241487 - gi\|75241487\|ref\|ZP_00725332.1\| COG1349: Transcriptional regulators of sugar metabolism [Escherichia ...	230.0	[0..1]	[250..11]
gi\|77975069, gi\|... - gi\|77975069\|ref\|ZP_00830606.1\| COG1349: Transcriptional regulators of sugar metabolism [Yersinia fre...	230.0	[0..3]	[250..1]

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Predicted Domain #1

Region A:
Residues: [1-66]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METRREERIG QLLQELKRSD KLHLKDAAAL LGVSEMTIRR DLNNHSAPVV LLGGYIVLEP  60
   61 RSASHY

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.21
Match:	1j5yA
Description:	Putative transcriptional regulator TM1602, N-terminal domain; Putative transcriptional regulator TM1602, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.67519658226073	bayes_pls_golite062009
DNA binding	3.1229077545522	bayes_pls_golite062009
nucleic acid binding	3.10431747895367	bayes_pls_golite062009
transcription factor activity	2.49694475728018	bayes_pls_golite062009
binding	2.03697617454396	bayes_pls_golite062009
transcription activator activity	0.293284204935948	bayes_pls_golite062009
sequence-specific DNA binding	0.266645609122554	bayes_pls_golite062009
transcription repressor activity	0.259857063944388	bayes_pls_golite062009
protein binding	0.00796693091603284	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [67-252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLSDQKSRLV EEKRRAAKLA ATLVEPDQTL FFDCGTTTPW IIEAIDNEIP FTAVCYSLNT  60
   61 FLALKEKPHC RAFLCGGEFH ASNAIFKPID FQQTLNNFCP DIAFYSAAGV HVSKGATCFN 120
  121 LEELPVKHWA MSMAQKHVLV VDHSKFGKVR PARMGDLKRF DIVVSDCCPE DEYVKYAQTQ 180
  181 RIKLMY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.69897
Match:	2pjmA
Description:	No description for 2pjmA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: