YRC Public Data Repository - Protein Structure Prediction

Protein:	ATPL_ECOLI
Organism:	Escherichia coli
Length:	79 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATPL_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|114581903 - gi\|114581903\|ref\|XP_525965.2\| PREDICTED: similar to mitochondrial ATP synthase subunit 9 precursor [...	1.0E-24	[3..78]	[207..281]
gi\|74004280 - gi\|74004280\|ref\|XP_545452.2\| PREDICTED: similar to ATP synthase, H+ transporting, mitochondrial F0 c...	3.0E-24	[3..78]	[319..393]
gi\|50750427 - gi\|50750427\|ref\|XP_426577.1\| PREDICTED: similar to Cg1746-prov protein [Gallus gallus]	6.0E-20	[3..78]	[255..329]
gi\|109096967 - gi\|109096967\|ref\|XP_001107007.1\| PREDICTED: ATP synthase, H+ transporting, mitochondrial F0 complex,...	3.0E-19	[3..78]	[124..198]
gi\|85794840, gi\|... - gi\|85794840\|ref\|NP_005167.2\| ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 iso... gi\|114644458 - gi\|114644458\|ref\|XP_509102.2\| PREDICTED: ATP synthase, H+ transporting, mitochondrial F0 complex, su...	9.0E-19	[3..78]	[124..198]
AT5G2_BOVIN - ATP synthase F(0) complex subunit C2, mitochondrial OS=Bos taurus GN=ATP5G2 PE=1 SV=1	5.0E-18	[3..78]	[69..143]
AT5G2_SHEEP - ATP synthase F(0) complex subunit C2, mitochondrial OS=Ovis aries GN=ATP5G2 PE=2 SV=1	6.0E-18	[3..78]	[69..143]
AT5G2_MOUSE - ATP synthase F(0) complex subunit C2, mitochondrial OS=Mus musculus GN=Atp5g2 PE=2 SV=2	7.0E-18	[3..78]	[72..146]

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Predicted Domain #1

Region A:
Residues: [1-79]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENLNMDLLY MAAAVMMGLA AIGAAIGIGI LGGKFLEGAA RQPDLIPLLR TQFFIVMGLV  60
   61 DAIPMIAVGL GLYVMFAVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.522879
Match:	1l6tA
Description:	F1F0 ATP synthase subunit c
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transmembrane transporter activity	11.0352537293656	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	9.29144499109826	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	8.21339437735436	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	7.77853842299952	bayes_pls_golite062009
cation-transporting ATPase activity	5.68769369232118	bayes_pls_golite062009
cation transmembrane transporter activity	4.52111403634053	bayes_pls_golite062009
ion transmembrane transporter activity	4.43965512012576	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.06187878627466	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	3.24700200659982	bayes_pls_golite062009
transporter activity	2.4278971299555	bayes_pls_golite062009
transmembrane transporter activity	2.3001871224946	bayes_pls_golite062009
substrate-specific transporter activity	2.23918161210694	bayes_pls_golite062009
primary active transmembrane transporter activity	1.88475786009787	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.8803631862627	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	1.85914623072813	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	1.85595665957922	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	1.85561719049428	bayes_pls_golite062009
active transmembrane transporter activity	1.80336965739382	bayes_pls_golite062009
ATPase activity, coupled	1.29142897805425	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.1760346488892	bayes_pls_golite062009
pyrophosphatase activity	1.11568144599728	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.10034526689676	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.09793714165961	bayes_pls_golite062009
ATPase activity	1.0557149464728	bayes_pls_golite062009
catalytic activity	0.60409960326459	bayes_pls_golite062009
hydrolase activity	0.320935567893193	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: