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View Structure Prediction Details

Protein: AMPC_ECOLI
Organism: Escherichia coli
Length: 377 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AMPC_ECOLI.

Description E-value Query
Range
Subject
Range
gi|4691722, gi|7... - gi|73809992|gb|AAZ85973.1| AmpC-EC13 [Escherichia coli], gi|4691724|gb|AAD28045.1|AF124205_1 beta-la...
370.0 [0..1] [377..1]
gi|75231253 - gi|75231253|ref|ZP_00717660.1| COG1680: Beta-lactamase class C and other penicillin binding proteins...
369.0 [0..1] [377..12]
gi|75188866 - gi|75188866|ref|ZP_00702133.1| COG1680: Beta-lactamase class C and other penicillin binding proteins...
368.0 [0..1] [377..12]

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Predicted Domain #1
Region A:
Residues: [1-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKTTLCALL ITASCSTFAA PQQINDIVHR TITPLIEQQK IPGMAVAVIY QGKPYYFTWG  60
   61 YADIAKKQPV TQQTLFELGS VSKTFTGVLG GDAIARGEIK LSDPTTKYWP ELTAKQWNGI 120
  121 TLLHLATYTA GGLPLQVPDE VKSSSDLLRF YQNWQPAWAP GTQRLYANSS IGLFGALAVK 180
  181 PSGLSFEQAM QTRVFQPLKL NHTWINVPPA EEKNYAWGYR EGKAVHVSPG ALDAEAYGVK 240
  241 STIEDMARWV QSNLKPLDIN EKTLQQGIQL AQSRYWQTGD MYQGLGWEML DWPVNPDSII 300
  301 NGSDNKIALA ARPVKAITPP TPAVRASWVH KTGATGGFGS YVAFIPEKEL GIVMLANKNY 360
  361 PNPARVDAAW QILNALQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 94.30103
Match: 1c3bA
Description: AMPC beta-Lactamase, class C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
beta-lactamase activity 6.11754430606414 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 4.78031291375234 bayes_pls_golite062009
peptidase activity 2.83039919794123 bayes_pls_golite062009
hydrolase activity 2.49793880633218 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.44010191138805 bayes_pls_golite062009
catalytic activity 2.2253600206851 bayes_pls_golite062009
serine-type peptidase activity 2.06335522739332 bayes_pls_golite062009
serine hydrolase activity 2.05686596429459 bayes_pls_golite062009
exopeptidase activity 1.47021212834188 bayes_pls_golite062009
carboxypeptidase activity 1.27821858943772 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.93520664618869 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle