YRC Public Data Repository - Protein Structure Prediction

Protein:	ALSE_ECOLI
Organism:	Escherichia coli
Length:	231 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALSE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|241884589, gi... - gi\|241902997\|ref\|ZP_04787726.1\| Ribulose-phosphate 3-epimerase [Thermoanaerobacter brockii subsp. fi... gi\|166854624, gi... - gi\|167040384\|ref\|YP_001663369.1\| ribulose-phosphate 3-epimerase [Thermoanaerobacter sp. X514], gi\|16... gi\|242231451, gi... - gi\|242257052\|ref\|ZP_04801929.1\| Ribulose-phosphate 3-epimerase [Thermoanaerobacter sp. X513], gi\|242... gi\|166856557, gi... - gi\|76797104\|ref\|ZP_00779444.1\| Ribulose-phosphate 3-epimerase [Thermoanaerobacter ethanolicus ATCC 3...	238.0	[0..1]	[219..1]
gi\|20807941 - gi\|20807941\|ref\|NP_623112.1\| Pentose-5-phosphate-3-epimerase [Thermoanaerobacter tengcongensis MB4] gi\|20807941, gi\|... - gi\|20807941\|ref\|NP_623112.1\| Pentose-5-phosphate-3-epimerase [Thermoanaerobacter tengcongensis MB4],...	233.0	[0..1]	[217..1]
gi\|71674917, gi\|... - gi\|71674917\|ref\|ZP_00672663.1\| Ribulose-phosphate 3-epimerase [Trichodesmium erythraeum IMS101], gi\|...	232.0	[0..1]	[216..9]
gi\|116058254 - gi\|116058254\|emb\|CAL53443.1\| GLUCOSE INHIBITED DIVISION PROTEIN A (ISS) [Ostreococcus tauri]	232.0	[0..1]	[230..45]
gi\|12722019, gi\|... - gi\|15603484\|ref\|NP_246558.1\| ribulose-phosphate 3-epimerase [Pasteurella multocida subsp. multocida ...	232.0	[0..3]	[218..21]
gi\|33865649, gi\|... - gi\|33865649\|ref\|NP_897208.1\| ribulose-phosphate 3-epimerase [Synechococcus sp. WH 8102], gi\|33632819...	231.0	[0..3]	[216..39]
gi\|47569486, gi\|... - gi\|47569486\|ref\|ZP_00240166.1\| ribulose-phosphate 3-epimerase [Bacillus cereus G9241], gi\|47553815\|g...	231.0	[0..1]	[214..2]
gi\|25292434 - pir\|\|AD1904 ribulose-phosphate 3-epimerase [imported] - Nostoc sp. (strain PCC 7120) gi\|17130127, gi\|... - gi\|17228277\|ref\|NP_484825.1\| ribulose-phosphate 3-epimerase [Nostoc sp. PCC 7120], gi\|17130127\|dbj\|B...	230.0	[0..1]	[216..10]
gi\|75910871, gi\|... - gi\|75910871\|ref\|YP_325167.1\| ribulose-phosphate 3-epimerase [Anabaena variabilis ATCC 29413], gi\|757...	230.0	[0..1]	[216..10]
gi\|59712895, gi\|... - gi\|59712895\|ref\|YP_205671.1\| ribulose-phosphate 3-epimerase [Vibrio fischeri ES114], gi\|59480996\|gb\|...	229.0	[0..3]	[222..6]

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Predicted Domain #1

Region A:
Residues: [1-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKISPSLMCM DLLKFKEQIE FIDSHADYFH IDIMDGHFVP NLTLSPFFVS QVKKLATKPL  60
   61 DCHLMVTRPQ DYIAQLARAG ADFITLHPET INGQAFRLID EIRRHDMKVG LILNPETPVE 120
  121 AMKYYIHKAD KITVMTVDPG FAGQPFIPEM LDKLAELKAW REREGLEYEI EVDGSCNQAT 180
  181 YEKLMAAGAD VFIVGTSGLF NHAENIDEAW RIMTAQILAA KSEVQPHAKT A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.30103
Match:	1tqjA
Description:	Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribulose-phosphate 3-epimerase activity	3.28372503209224	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
intramolecular oxidoreductase activity	1.86158562896415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.36492964250879	bayes_pls_golite062009
isomerase activity	0.935800409577999	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.764608070506109	bayes_pls_golite062009
orotidine-5'-phosphate decarboxylase activity	0.758594564254247	bayes_pls_golite062009
binding	0.595171555788202	bayes_pls_golite062009
racemase and epimerase activity	0.288948763149344	bayes_pls_golite062009
carboxy-lyase activity	0.1100847613283	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: