| Protein: | acr-20 |
| Organism: | Caenorhabditis elegans |
| Length: | 514 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-20.
| Description | E-value | Query Range |
Subject Range |
|
|
390.0 | [0..2] | [511..44] |
|
Region A: Residues: [1-180] |
1 11 21 31 41 51
| | | | | |
1 MGKKSPIEVH FSMELYQIIS VNEPQQFLML NAWVVERWTD RLLGWDPEKF GNVTEIMLPH 60
61 HFIWLPDTTL YNSLVMKDDE NRRLLHAKVT TLGEGNGAFI ELLYPTIYKL SCLLNLRFFP 120
121 FDVQSCRLLF GSWTFDNTKI DYFAFNESQA IGTTNCIENE GWNVLSTSVI RHENKYDCCP 180
181
|
| Detection Method: |  |
| Confidence: | 66.39794 |
| Match: | 2bg9E |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [181-514] |
1 11 21 31 41 51
| | | | | |
1 NNYTLLEFRL TIQRKPLYYI INLIIPTSII TFISIIGFFS TSSINEPREE KITLGITTLL 60
61 SMSILIFMVS DKMPSTSSFI PLIGLFYTSM ILLISFSTIC SSVVIYVQKQ GNLGNPPSKN 120
121 FMNIARAVNR FIRMEMPLIM KQAYAQKARE EKLRRQQMGR KQSLWTRVYK LAREQALRKD 180
181 VQTSQNSSKF NEVLTPEKLI DNGGKRCTIN KDVTCISDSG IVAMGVPTLA SEDDDQDVSL 240
241 LELETTPTPA MQRPTRLHKA STCGSFDSMM FRQIEVPVSP RTARNLAEIE YDWLAALLER 300
301 IFLITFLFIF VLTSIGINLI GFFYWWMAPD TVRV
|
| Detection Method: | |
| Confidence: | 35.69897 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| extracellular ligand-gated ion channel activity | 6.56684020745942 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 6.56684020745942 | bayes_pls_golite062009 |
| acetylcholine binding | 6.52442204852986 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 6.36289790201154 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 6.18186125255445 | bayes_pls_golite062009 |
| amine binding | 5.41519146716044 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 4.11436828514898 | bayes_pls_golite062009 |
| neurotransmitter binding | 3.8955866963605 | bayes_pls_golite062009 |
| ligand-gated channel activity | 3.89042942026915 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 3.89042942026915 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 3.85109091742077 | bayes_pls_golite062009 |
| channel activity | 3.85109091742077 | bayes_pls_golite062009 |
| gated channel activity | 3.78736801121715 | bayes_pls_golite062009 |
| ion channel activity | 3.74897051183521 | bayes_pls_golite062009 |
| substrate-specific channel activity | 3.71266288521973 | bayes_pls_golite062009 |
| cation channel activity | 3.63600692930143 | bayes_pls_golite062009 |
| signal transducer activity | 2.79604294798446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.79604294798446 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.68988479891625 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.2664383168765 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.15975795305845 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.86141735260141 | bayes_pls_golite062009 |
| binding | 1.79555479138162 | bayes_pls_golite062009 |
| receptor activity | 1.7530052047317 | bayes_pls_golite062009 |
| chloride channel regulator activity | 1.70228013722122 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 1.66164195684481 | bayes_pls_golite062009 |
| channel regulator activity | 1.19940273232477 | bayes_pls_golite062009 |
| 1.14757191423748 | bayes_pls_golite062009 | |
| transporter activity | 0.768184565846134 | bayes_pls_golite062009 |
| beta-amyloid binding | 0.60757966423936 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.601789813334198 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.405772730772208 | bayes_pls_golite062009 |
| protein binding | 0.174311879345146 | bayes_pls_golite062009 |
