| Protein: | VPS8 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1274 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS8.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [2..1274] | [2..1274] |
|
|
0.0 | [10..1269] | [2..1214] |
|
|
0.0 | [66..1264] | [196..1592] |
|
|
0.0 | [8..1269] | [106..1291] |
|
|
0.0 | [86..1229] | [217..1511] |
|
|
0.0 | [59..1269] | [48..1230] |
|
|
0.0 | [66..1256] | [199..1554] |
|
|
0.0 | [101..1268] | [81..1346] |
|
Region A: Residues: [1-450] |
1 11 21 31 41 51
| | | | | |
1 MEQNGLDHDS RSSIDTTIND TQKTFLEFRS YTQLSEKLAS SSSYTAPPLN EDGPKGVASA 60
61 VSQGSESVVS WTTLTHVYSI LGAYGGPTCL YPTATYFLMG TSKGCVLIFN YNEHLQTILV 120
121 PTLSEDPSIH SIRSPVKSIV ICSDGTHVAA SYETGNICIW NLNVGYRVKP TSEPTNGMTP 180
181 TPALPAVLHI DDHVNKEITG LDFFGARHTA LIVSDRTGKV SLYNGYRRGF WQLVYNSKKI 240
241 LDVNSSKEKL IRSKLSPLIS REKISTNLLS VLTTTHFALI LLSPHVSLMF QETVEPSVQN 300
301 SLVVNSSISW TQNCSRVAYS VNNKISVISI SSSDFNVQSA SHSPEFAESI LSIQWIDQLL 360
361 LGVLTISHQF LVLHPQHDFK ILLRLDFLIH DLMIPPNKYF VISRRSFYLL TNYSFKIGKF 420
421 VSWSDITLRH ILKGDYLGAL EFIESLLQPY
|
| Detection Method: |  |
| Confidence: | 40.69897 |
| Match: | 1nr0A_ |
| Description: | Actin interacting protein 1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.8484919978091 | bayes_pls_golite062009 |
| protein binding | 1.42618832381942 | bayes_pls_golite062009 |
| transporter activity | 1.21549336905926 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.734793983890004 | bayes_pls_golite062009 |
| hydrolase activity | 0.36638536879917 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.359536347486199 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.00585398682921312 | bayes_pls_golite062009 |
|
Region A: Residues: [451-638] |
1 11 21 31 41 51
| | | | | |
1 CPLANLLKLD NNTEERTKQL MEPFYNLSLA ALRFLIKKDN ADYNRVYQLL MVVVRVLQQS 60
61 SKKLDSIPSL DVFLEQGLEF FELKDNAVYF EVVANIVAQG SVTSISPVLF RSIIDYYAKE 120
121 ENLKVIEDLI IMLNPTTLDV DLAVKLCQKY NLFDLLIYIW NKIFDDYQTP VVDLIYRISN 180
181 QSEKCVIF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [639-772] |
1 11 21 31 41 51
| | | | | |
1 NGPQVPPETT IFDYVTYILT GRQYPQNLSI SPSDKCSKIQ RELSAFIFSG FSIKWPSNSN 60
61 HKLYICENPE EEPAFPYFHL LLKSNPSRFL AMLNEVFEAS LFNDDNDMVA SVGEAELVSR 120
121 QYVIDLLLDA MKDT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [773-1091] |
1 11 21 31 41 51
| | | | | |
1 GNSDNIRVLV AIFIATSISK YPQFIKVSNQ ALDCVVNTIC SSRVQGIYEI SQIALESLLP 60
61 YYHSRTTENF ILELKEKNFN KVLFHIYKSE NKYASALSLI LETKDIEKEY NTDIVSITDY 120
121 ILKKCPPGSL ECGKVTEVIE TNFDLLLSRI GIEKCVTIFS DFDYNLHQEI LEVKNEETQQ 180
181 KYLDKLFSTP NINNKVDKRL RNLHIELNCK YKSKREMILW LNGTVLSNAE SLQILDLLNQ 240
241 DSNFEAAAII HERLESFNLA VRDLLSFIEQ CLNEGKTNIS TLLESLRRAF DDCNSAGTEK 300
301 KSCWILLITF LITLYGKYP
|
| Detection Method: | |
| Confidence: | 13.30103 |
| Match: | 1b89A_ |
| Description: | Clathrin heavy chain proximal leg segment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1092-1190] |
1 11 21 31 41 51
| | | | | |
1 SHDERKDLCN KLLQEAFLGL VRSKSSSQKD SGGEFWEIMS SVLEHQDVIL MKVQDLKQLL 60
61 LNVFNTYKLE RSLSELIQKI IEDSSQDLVQ QYRKFLSEG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1191-1274] |
1 11 21 31 41 51
| | | | | |
1 WSIHTDDCEI CGKKIWGAGL DPLLFLAWEN VQRHQDMISV DLKTPLVIFK CHHGFHQTCL 60
61 ENLAQKPDEY SCLICQTESN PKIV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.13191655110108 | bayes_pls_golite062009 |
| protein binding | 1.69332800381364 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 1.19185232032795 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.18697373227452 | bayes_pls_golite062009 |
| hydrolase activity | 0.737434311410924 | bayes_pls_golite062009 |
| catalytic activity | 0.168711389690753 | bayes_pls_golite062009 |
| peptidase activity | 0.0046487386791938 | bayes_pls_golite062009 |
