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View Structure Prediction Details

Protein: HXK3_ARATH
Organism: Arabidopsis thaliana
Length: 498 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXK3_ARATH.

Description E-value Query
Range
Subject
Range
gi|30961939 - gi|30961939|gb|AAP40021.1| hexokinase [Nicotiana benthamiana]
611.0 [0..1] [497..1]

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Predicted Domain #1
Region A:
Residues: [1-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKVAVAFAA VAVVAACSVA AVMVGRRMKS RRKWRTVVEI LKELEDDCDT PVGRLRQVVD  60
   61 AMAVEMHAGL ASEGGSKLKM LLTFVDDLPT GREKGTYYAL HLGGTYFRIL RVLLGDQRSY 120
  121 LDVQDVERHP IPSHLMNSTS EVLFNFLAFS LERFIEKEEN GSDSQGVRRE LAFTFSFPVK 180
  181 HTSISSGVLI KWTKGFEISE MVGQDIAECL QGALNRRGLD MHVAALVNDT VGALSLGYYH 240
  241 DPDTVVAVVF GTGSNACYLE RTDAIIKCQG LLTTSGSMVV NMEWGNFWSS HLPRTSYDID 300
  301 LDAESSNAND MGFEKMISGM YLGDIVRRVI LRMSEDSDIF GPISPVLSEP YVLRTNSVSA 360
  361 IHEDDTPELQ EVARILKDIG VSDVPLKVRK LVVKICDVVT RRAGRLAAAG IAGILKKIGR 420
  421 DGSGGITSGR SRSEIQMQKR TVVAVEGGLY MNYTMFREYM EEALVEILGE EVSQYVVVKA 480
  481 MEDGSSIGSA LLVASLQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 157.0
Match: 1czaN
Description: Mammalian type I hexokinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
carbohydrate kinase activity 2.33338276303563 bayes_pls_golite062009
binding 2.11855816699924 bayes_pls_golite062009
transcription regulator activity 2.09111975841662 bayes_pls_golite062009
nucleic acid binding 1.84294882554466 bayes_pls_golite062009
hexokinase activity 1.70516840340504 bayes_pls_golite062009
DNA binding 1.70014394990425 bayes_pls_golite062009
structural molecule activity 1.16294507971847 bayes_pls_golite062009
kinase activity 1.11102445353265 bayes_pls_golite062009
transcription factor activity 1.06678984888387 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.00147083605664 bayes_pls_golite062009
protein binding 0.956664772028256 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.795304313835604 bayes_pls_golite062009
mannokinase activity 0.766256764215041 bayes_pls_golite062009
glucokinase activity 0.47468456642723 bayes_pls_golite062009
glucose binding 0.31060748948812 bayes_pls_golite062009
catalytic activity 0.296484721581333 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.262962195214361 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.261888708156649 bayes_pls_golite062009
pyrophosphatase activity 0.238942225029338 bayes_pls_golite062009
monosaccharide binding 0.20435276425198 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.118897949447288 bayes_pls_golite062009
transferase activity 0.105619024604158 bayes_pls_golite062009
unfolded protein binding 0.0304569608189402 bayes_pls_golite062009
transcription activator activity 0.0275592755061818 bayes_pls_golite062009

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