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View Structure Prediction Details

Protein: gi|2832704, gi|7...
Organism: Arabidopsis thaliana
Length: 709 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2832704, gi|7....

Description E-value Query
Range
Subject
Range
EI2BE_RAT - Translation initiation factor eIF-2B subunit epsilon OS=Rattus norvegicus GN=Eif2b5 PE=1 SV=2
gi|55741628 - ref|NP_620221.2| initiation factor eIF-2Be [Rattus norvegicus]
357.0 [0..3] [708..8]

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Predicted Domain #1
Region A:
Residues: [1-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAQKKPAAA KVREDSEDLS RQRLQAILLA DSFTTQFRSI TLERPKVLLP IVNIPMIDYT  60
   61 LAWLESAGIE EVFVFCCAHS SQIIDYLKKS EWYTRPNPNL LVRTIVSHNS TSVGDALRYI 120
  121 YEQQTETSQI QGDFVLVSGD TVSNMPLADL IQQHRDRKKK DEKAIMTMVF KKQSRLGIGS 180
  181 DQLFVAVDPL TKQLLHYEEC NSRGGDFCLD KSLLDSTVLC SDMQDCYIDI CSPEVLSLFE 240
  241 DNFDYQHMRR HFVNGLLVDD IMGYKIFTHE IQSSCYAARI DNLRSYDTVS KDIIQRWTYP 300
  301 YVPNIDFSGN RPVKLGRRGI YRASDAVQSH TADVGASTVI GYGTKIGNGG KIYNSVIGNG 360
  361 CCIGSNVVIQ GSYIWNNVTI EDGCEIRNAI VCDGVKVRAG AVLQPGVVLS FSVVVGRDFV 420
  421 VPAYSKVSLL QQPTTEDSDE ELEYADSSSG TADHSSGLNN LQIESKASEL GPDGAGYIWE 480
  481 ICDSAHDEEW KHSVVP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.09691
Match: 1hv9A
Description: N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity 2.17535315350752 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
nucleotidyltransferase activity 1.86990263440735 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.49149681135671 bayes_pls_golite062009
binding 1.09657219604879 bayes_pls_golite062009
protein binding 0.967722609820275 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.796949457473955 bayes_pls_golite062009
acyltransferase activity 0.741838450922005 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 0.717805296858439 bayes_pls_golite062009
UDP-glycosyltransferase activity 0.619458068514795 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.555398952276587 bayes_pls_golite062009
O-acyltransferase activity 0.319932817519902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [497-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPMDKLADIT GAMDDDDIED DIVVPPSGEL KSDTDIINTD ANDSYGDFER EVEEEFLSAV  60
   61 EKDNKADIVI PLINSHRLAY NMDSADCAGA VFYSMMRLAV KSPHNSATEL YRNAMGVITK 120
  121 WKGVLGFYLK QTDAQIEVIM KFEEMCQESE ELSPLFAKLL PFLYDKDVVQ EDAILRWGEE 180
  181 KAGADDCDKV YLNKCESFIK WLKEASEEEE EDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.0
Match: 1paqA
Description: CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF EUKARYOTIC INITIATION FACTOR 2B EPSILON
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 9.37171190530754 bayes_pls_golite062009
translation regulator activity 5.35226950142169 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
protein binding 2.78733902345842 bayes_pls_golite062009
nucleic acid binding 2.34284977509828 bayes_pls_golite062009
transcription regulator activity 1.76231475025891 bayes_pls_golite062009
RNA cap binding 1.73309326409609 bayes_pls_golite062009
DNA binding 1.62032607987786 bayes_pls_golite062009
transcription activator activity 1.23830945970239 bayes_pls_golite062009
transcription factor activity 0.923253759652909 bayes_pls_golite062009
structural molecule activity 0.908029258648777 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.803700928110921 bayes_pls_golite062009
mRNA binding 0.46864854653143 bayes_pls_golite062009
RNA binding 0.40024158562931 bayes_pls_golite062009
protein phosphatase binding 0.18767619609331 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle