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Protein Overview: EI2BE_RAT

General Information:
Name(s) found: EI2BE_RAT [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • Translation initiation factor eIF-2B subunit epsilon OS=Rattus norvegicus GN=Eif2b5 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 716 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    cytoplasm [UNKNOWN][ISS]
    eukaryotic translation initiation factor 2B complex [UNKNOWN][IDA][ISS][TAS]
    Biological Process: positive regulation of translational initiation [ISS]
    oligodendrocyte development [UNKNOWN][ISS]
    astrocyte development [UNKNOWN][ISS]
    astrocyte differentiation [UNKNOWN][ISS]
    myelination [UNKNOWN][ISS]
    translational initiation [UNKNOWN][ISS][TAS]
    response to peptide hormone stimulus [IDA]
    response to stress [UNKNOWN][ISS]
    ovarian follicle development [UNKNOWN][ISS]
    regulation of translation [IMP]
    response to heat [UNKNOWN][IDA][ISS]
    response to glucose stimulus [IDA]
    cellular response to stimulus [UNKNOWN][ISS]
    negative regulation of translational initiation in response to stress [IMP]
    Molecular Function: translation initiation factor activity [UNKNOWN][ISS][TAS]
    protein binding [UNKNOWN][IPI]
    guanyl-nucleotide exchange factor activity [UNKNOWN][IDA][IMP][ISS]
    transferase activity [IEA]
    translation initiation factor binding [IDA][IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATAAVPSA VGGRANKRGG GSGGGGTQGA EEEPPPPLQA VLVADSFDRR FFPISKDQPR  60
   61 VLLPLANVAL IDYTLEFLTA TGVQETFVFC CWKAAQIKEH LQKSKWCHPT SLNVVRIITS 120
  121 DLYRSLGDVL RDVDAKALVR SDFLLIYGDV VSNINISKAL EEHRLRRKLE KNVSVMTMVF 180
  181 KESSPSHPTR CHEDNVVLAV DSTTNRILHF QKTQGLRHFS FPLGLFQGSL DGVEIRYDLL 240
  241 DCHISICSPQ VAQLFTDNFD YQTRDDFVRG LLVNEEILGN QIHLHVTSRE YGARVSNLHM 300
  301 YSAVCADVIR RWVYPLTPEV NFTDSSTQSY THSRHNIYRG PEVSLGHGSV LEENVLLGAG 360
  361 TVVGSNCSIT NSVIGPNCHI GDNVVLDQAY LWQGVRVAAG AQIHQSLLCD RAEVKERVIL 420
  421 KPHCVLTSQV VVGPDIILPE GSVISLHPPD AEEDEDDGQF SDDSGADQEK EKVKLKGYNP 480
  481 AEVGPEGQGY LWKAEDVDEK EDEELRQSLW GLMINMEEES ETESERSVDP EELDSRAGSP 540
  541 QLDDIRVFQN EVLGTLQRGR EENISCDNLV LEINSLKYAY NISLKEVMQV LSHVVLEFPL 600
  601 QQVDGVLDPN RYCALLLPLL KAWSPVFRNY IKRAADHLEA LAAIEDFFLE HETLVPSLAK 660
  661 VLMAFYQLEI LAEETILSWF SQRDITDKGQ QLRKNQQLQR FIQWLREAEE ESSDDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle