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View Structure Prediction Details

Protein: gi|15222423, gi|...
Organism: Arabidopsis thaliana
Length: 1028 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15222423, gi|....

Description E-value Query
Range
Subject
Range
gi|79512157 - gi|79512157|ref|NP_568268.2| Ran GTPase binding / chromatin binding / zinc ion binding [Arabidopsis ...
617.0 [0..1] [1027..1]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADSLRTSFS ERDVEQAITS LKKGSYLLKY GRRGKPKFCP FQLTSDESAL VWYSGKEEKQ  60
   61 IKLSQVLRIV PGQRTPTFKR YPRPEKEYQS FSLICPDRSL DLICKDKDEA EVWVVGLKSL 120
  121 ITRVKVSKWK TTIKPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1maiA
Description: STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM PHOSPHOLIPASE C DELTA IN COMPLEX WITH INOSITOL TRISPHOSPHATE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.29080729281876 bayes_pls_golite062009
cytoskeletal protein binding 2.48216092627697 bayes_pls_golite062009
actin binding 2.31347896928633 bayes_pls_golite062009
protein binding 2.12168271674167 bayes_pls_golite062009
actin filament binding 0.636262824984581 bayes_pls_golite062009
transcription regulator activity 0.324566338715835 bayes_pls_golite062009
DNA binding 0.136435190086451 bayes_pls_golite062009
nucleic acid binding 0.118897432176337 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [137-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITSAECPTPH ARRVSPFVTI LDQVIQPSNE TSTQTRLGKV FSDIVAITAP PSNNNQTEAS  60
   61 GN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [199-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFCPFSPTPA NVENSNLRFS TNDPFRLSLS SAVSTSSHGS YHEDFDALGD VFVWGESISD  60
   61 GVLSGTGNSL NSTTEDALLP KALESTIVLD AQNIACGKCH AVLVTKQGEI FSWGEGKGGK 120
  121 LGHGLETDAQ KPKFISSVRG LGFKSLACGD FHTCAITQSG DLYSWGDGTH NVDLLGHGNE 180
  181 SSCWIPKRVT GDLQGLYVSD VACGPWHTAV VASSGQLFTF GDGTFGALGH GDRRSTSVPR 240
  241 EVESLIGLIV TKVACGVWHT AAVVEVTNEA SEAEVDSSRG QVFTWGDGEK GQLGHGDNDT 300
  301 KLLPECVISL TNENICQVAC GHSLTVSRTS RGHVYTMGST AYGQLGNPTA KGNFPERVEG 360
  361 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.0
Match: 1a12A
Description: Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
Ran guanyl-nucleotide exchange factor activity 1.99390987036621 bayes_pls_golite062009
binding 1.94765972306941 bayes_pls_golite062009
GTPase regulator activity 0.902045197448864 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.881338215451345 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.732530371959803 bayes_pls_golite062009
small GTPase regulator activity 0.676767309840836 bayes_pls_golite062009
Ras guanyl-nucleotide exchange factor activity 0.623383363250545 bayes_pls_golite062009
protein binding 0.568399753749593 bayes_pls_golite062009
enzyme regulator activity 0.510366022767141 bayes_pls_golite062009
chromatin binding 0.22692195000219 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [559-1028]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIVEASVEEI ACGSYHVAVL TSKSEIYTWG KGLNGQLGHG NVENKREPAV VGFLREKQVK  60
   61 AITCGSNFTA VICVHKWVPG SEHSLCAGCR NPFNFRRKRH NCYNCGLVFC KVCSSRKSLR 120
  121 AALAPDMNKP YRVCYGCFTK LKKSRESSPS TPTSRTRKLL NMRKSTDVSE RDSLTQKFLS 180
  181 VNARLSSADS SLHYSERRHH RRDLKPEVNN SNVFPSMNGS LQPVGSPFSK GSTALPKIPK 240
  241 NMMVKIPGSG MSSRTTSPVS VKSTSPRRSY EVAAAESKQL KDSFNQDMAG LKEQVEQLAS 300
  301 KAHQLEEELE KTKRQLKVVT AMAADEAEEN RSAKEVIRSL TTQLKEMAEK QSQKDSISTN 360
  361 SKHTDKEKSE TVTQTSNQTH IRSMVSQDSQ NENNLTSKSF ANGHRKQNDK PEKVVQDEPG 420
  421 VYLTLLSLPG GGTELKRVRF SRKQFTEEQA EKWWGENGAK VCERHNILVS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle