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View Structure Prediction Details

Protein: DLDH1_ARATH
Organism: Arabidopsis thaliana
Length: 507 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DLDH1_ARATH.

Description E-value Query
Range		 Subject
Range
gi|8778521, gi|2... - gi|8778521|gb|AAF79529.1|AC023673_17 F21D18.28 [Arabidopsis thaliana], pir||F96520 dihydrolipoamide ...
 443.0 [0..3] [507..1]

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Predicted Domain #1
Region A:
Residues: [1-507] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMASLARRK AYFLTRNLSN SPTDALRFSF SLSRGFASSG SDENDVVIIG GGPGGYVAAI  60
   61 KASQLGLKTT CIEKRGALGG TCLNVGCIPS KALLHSSHMY HEAKHSFANH GIKVSSVEVD 120
  121 LPAMLAQKDN AVKNLTRGIE GLFKKNKVTY VKGYGKFISP NEVSVETIDG GNTIVKGKHI 180
  181 IVATGSDVKS LPGITIDEKK IVSSTGALSL SEVPKKLIVI GAGYIGLEMG SVWGRLGSEV 240
  241 TVVEFAGDIV PSMDGEIRKQ FQRSLEKQKM KFMLKTKVVS VDSSSDGVKL TVEPAEGGEQ 300
  301 SILEADVVLV SAGRTPFTSG LDLEKIGVET DKAGRILVND RFLSNVPGVY AIGDVIPGPM 360
  361 LAHKAEEDGV ACVEFIAGKH GHVDYDKVPG VVYTHPEVAS VGKTEEQLKK EGVSYRVGKF 420
  421 PFMANSRAKA IDNAEGLVKI LADKETDKIL GVHIMAPNAG ELIHEAVLAI NYDASSEDIA 480
  481 RVCHAHPTMS EALKEAAMAT YDKPIHI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 112.0
Match: 1dxlA
Description: Dihydrolipoamide dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 8.07008457237017 bayes_pls_golite062009
lipoamide binding 7.21320397413054 bayes_pls_golite062009
pyruvate dehydrogenase activity 6.59152030973708 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 6.56425883527182 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 6.2758493127081 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 6.2758493127081 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 6.01050580930819 bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity 5.38255966064925 bayes_pls_golite062009
oxoglutarate dehydrogenase (succinyl-transferring) activity 5.32373368820399 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 5.18991258719053 bayes_pls_golite062009
NADH dehydrogenase activity 3.68406278988218 bayes_pls_golite062009
thioredoxin-disulfide reductase activity 3.42654162439464 bayes_pls_golite062009
antioxidant activity 3.37477730756688 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 3.35142373392777 bayes_pls_golite062009
oxidoreductase activity 3.19495080984613 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 3.17769237742078 bayes_pls_golite062009
oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor 3.15456908604913 bayes_pls_golite062009
glutathione binding 2.84679371365652 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.57282017498189 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.50603438449246 bayes_pls_golite062009
oxidoreductase activity, oxidizing metal ions 2.49798084628282 bayes_pls_golite062009
tubulin binding 2.40546880499445 bayes_pls_golite062009
microtubule binding 2.30064869971937 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.28982462439281 bayes_pls_golite062009
cytoskeletal protein binding 2.23446140524739 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.12515648558024 bayes_pls_golite062009
catalytic activity 1.56773888754354 bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity 1.42994468012845 bayes_pls_golite062009
binding 1.4227698123368 bayes_pls_golite062009
protein binding 1.16738144711505 bayes_pls_golite062009
transporter activity 0.890824576391732 bayes_pls_golite062009
transmembrane transporter activity 0.706117386114413 bayes_pls_golite062009
NADPH-adrenodoxin reductase activity 0.684108511779641 bayes_pls_golite062009
transferase activity 0.565295320107724 bayes_pls_golite062009
electron carrier activity 0.511623955786613 bayes_pls_golite062009
substrate-specific transporter activity 0.491481205015383 bayes_pls_golite062009
coenzyme binding 0.424849261981 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.26114823844682 bayes_pls_golite062009
succinate dehydrogenase activity 0.110826254138262 bayes_pls_golite062009
disulfide oxidoreductase activity 0.0160065137614933 bayes_pls_golite062009
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