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View Structure Prediction Details

Protein: NICA_ARATH
Organism: Arabidopsis thaliana
Length: 676 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NICA_ARATH.

Description E-value Query
Range
Subject
Range
gi|114560633 - gi|114560633|ref|XP_001171686.1| PREDICTED: nicastrin isoform 2 [Pan troglodytes]
529.0 [0..4] [676..16]

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Predicted Domain #1
Region A:
Residues: [1-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMGLIRLLS IAFTLVLLSI LPLHLSLADE ITSIESVPDL QKLMYVAVDG FPCVRLLNLS  60
   61 GEIGCSNPGI NKVVAPIIKL KDVKDLVQPH TILVTADEME DFFTRVSTDL SFASKIGGVL 120
  121 VESGSNFQQK LKGFSPDKRF PQAQFSPYEN VEYKWNSAAS SIMWRNYNFP VYLLSESGIS 180
  181 AVHEILSKKK MKHGTYTSDV AEFNMVMETT KAGTHNSEAC LQEGTCLPLG GYSVWSSLPP 240
  241 ISVSSSNNRK PVVLTVASMD TASFFRDKSF GADSPISGLV ALLGAVDALS RVDGISNLKK 300
  301 QLVFLVLTGE TWGYLGSRRF LHELDLHSDA VAGLSNTSIE TVLEIGSVGK GLSGGINTFF 360
  361 AHKTRVSSVT NMTLDALKIA QDSLASKNIK ILSADTANPG IPPSSLMAFM RKNPQTSAVV 420
  421 LEDFDTNFVN KFYHSHLDDL SNINSSSVVA AASVVARTLY ILASDNKDTS NSALGSIHVN 480
  481 ASFVEELLTC LLACEPGLSC NLVKDYISPT NTCPGNYAGV ILGEPSSKPY LGYVGDVSRF 540
  541 LWNFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 2ootA
Description: No description for 2ootA was found.

Predicted functions:

Term Confidence Notes
transmembrane receptor activity 3.68442839136734 bayes_pls_golite062009
peptidase activity 3.64510404037841 bayes_pls_golite062009
receptor activity 3.43249110530054 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.26499474130077 bayes_pls_golite062009
hydrolase activity 2.98013991489506 bayes_pls_golite062009
signal transducer activity 2.61784313760368 bayes_pls_golite062009
molecular transducer activity 2.61784313760368 bayes_pls_golite062009
metallopeptidase activity 2.04062448553328 bayes_pls_golite062009
exopeptidase activity 1.70361627875478 bayes_pls_golite062009
catalytic activity 1.3989281287879 bayes_pls_golite062009
metalloexopeptidase activity 0.950629204175701 bayes_pls_golite062009
carboxypeptidase activity 0.891655769761122 bayes_pls_golite062009
binding 0.688905385320691 bayes_pls_golite062009
metallocarboxypeptidase activity 0.180859448845431 bayes_pls_golite062009
protein binding 0.00854198798870509 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [546-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADKTSVQKGN TTSVCSKGVC SKTDEVCIKA ESNKEGTCVV STTRYVPAYS TRLKYNDGAW  60
   61 TILPQNSSDS MGMVDPVWTE SNWDTLRVHV YTVQHSAYDN AVLVAGITVT TLAYIGILAA 120
  121 KSIITKALKQ D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle