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View Structure Prediction Details

Protein: GCP1_ARATH
Organism: Arabidopsis thaliana
Length: 376 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCP1_ARATH.

Description E-value Query
Range
Subject
Range
gi|186516984, gi... - gi|186516984|ref|NP_195406.2| CP1 (CYSTEINE PROTEINASE1); cysteine-type endopeptidase/ cysteine-type...
369.0 [0..1] [376..1]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPSTKVLSL LLLYVVVSLA SGDESIINDH LQLPSDGKWR TDEEVRSIYL QWSAEHGKTN  60
   61 NNNNGIINDQ DKRFNIFKDN LRFIDLHNED NKNATYKLGL TKFTDLTNDE YRKLYLGART 120
  121 EPARRIAKAK N

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.97
Match: 1by8A
Description: (Pro)cathepsin K
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [132-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNQKYSAAVN GKEVPETVDW RQKGAVNPIK DQGTCGSCWA FSTTAAVEGI NKIVTGELIS  60
   61 LSEQELVDCD KSYNQGCNGG LMDYAFQFIM KNGGLNTEKD YPYRGFGGKC NSFLKNSRVV 120
  121 SIDGYEDVPT KDETALKKAI SYQPVSVAIE AGGRIFQHYQ SGIFTGSCGT NLDHAVVAVG 180
  181 YGSENGVDYW IVRNSWGPRW GEEGYIRMER NLAASKSGKC GIAVEASYPV KYSPNPVRGN 240
  241 TISSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.522879
Match: 1s4vA
Description: The 2.0 A crystal structure of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.90619850296986 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.64381885397949 bayes_pls_golite062009
endopeptidase activity 3.75054525912786 bayes_pls_golite062009
hydrolase activity 3.74079711298952 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
binding 1.29265216891074 bayes_pls_golite062009
cytoskeletal protein binding 1.12653729823589 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.774177093888744 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.649171767629235 bayes_pls_golite062009
thiolester hydrolase activity 0.59115205419466 bayes_pls_golite062009
kininogen binding 0.41283715939055 bayes_pls_golite062009
signal transducer activity 0.12644030784065 bayes_pls_golite062009
molecular transducer activity 0.12644030784065 bayes_pls_golite062009
structural molecule activity 0.102555314244558 bayes_pls_golite062009
tubulin binding 0.0482209771629902 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009
microtubule binding 0.00635493133568055 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle