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View Structure Prediction Details

Protein: CALX2_ARATH
Organism: Arabidopsis thaliana
Length: 532 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CALX2_ARATH.

Description E-value Query
Range
Subject
Range
CALX1_ARATH - Calnexin homolog 1 OS=Arabidopsis thaliana GN=CNX1 PE=1 SV=1
644.0 [0..1] [532..1]

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Predicted Domain #1
Region A:
Residues: [1-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRERIITFVS LLLVALLSFP SVSYCDDQTI LYESFDEPFD GRWVVSEKAE YQGVWKHEKS  60
   61 EGHDDYGLLV SEKAKKYGIV KELDVDEPLN LNEGTVVLQY EARFQEGLEC GGAYLKYLRP 120
  121 QEAGWVPQGF DNDSPYSIMF GPDKCGATNK VHFILKHKNP KSGEFVEHHL KFPPSVPFDM 180
  181 LSHVYTAVLK SDNEVRILVD GEEKKKGNLL SAEDFEPPLI PSKTIPDPED KKPEDWDERA 240
  241 KIPDPNAVKP DDWDEDAPME IEDEEAEKPE GWLDDEPVEV EDPEASKPED WDDEEDGEWE 300
  301 APKVSNTKCE AAPGCGEWKR PMKRNPAYKG KWSSPLIDNP AYKGIWKPRD IPNPDYFELE 360
  361 RPNLEPIAAI GIEIWTMQDG ILFDNILISK DEKVAETYRQ STWKPKFDVE KEKQKAEDEA 420
  421 A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 154.0
Match: 1jhnA
Description: Calnexin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
complement component C1q binding 4.81971897425786 bayes_pls_golite062009
steroid hormone receptor binding 4.11346029337178 bayes_pls_golite062009
androgen receptor binding 3.88449123711676 bayes_pls_golite062009
zymosan binding 3.41405218556083 bayes_pls_golite062009
nuclear hormone receptor binding 3.3517714661273 bayes_pls_golite062009
binding 3.24845777545007 bayes_pls_golite062009
hormone receptor binding 3.2405597896178 bayes_pls_golite062009
structural molecule activity 3.0286932947016 bayes_pls_golite062009
unfolded protein binding 2.94586353433162 bayes_pls_golite062009
protein binding 2.62442480878692 bayes_pls_golite062009
transcription regulator activity 2.5786381493734 bayes_pls_golite062009
transcription repressor activity 2.42862869142896 bayes_pls_golite062009
nucleic acid binding 2.33705817770533 bayes_pls_golite062009
cytoskeletal protein binding 2.16616430987996 bayes_pls_golite062009
actin binding 2.0669297251683 bayes_pls_golite062009
DNA binding 2.05388036301171 bayes_pls_golite062009
carbohydrate binding 1.90829797790335 bayes_pls_golite062009
sugar binding 1.89824804892868 bayes_pls_golite062009
receptor binding 1.70102429470678 bayes_pls_golite062009
cation binding 1.67588357161378 bayes_pls_golite062009
metal ion binding 1.67588357161378 bayes_pls_golite062009
ion binding 1.66900324045723 bayes_pls_golite062009
NACHT domain binding 1.53382521801494 bayes_pls_golite062009
integrin binding 1.36513827550387 bayes_pls_golite062009
transporter activity 1.29150662073327 bayes_pls_golite062009
chaperone binding 1.28860282614448 bayes_pls_golite062009
glycosaminoglycan binding 1.25720635817943 bayes_pls_golite062009
signal transducer activity 1.24423621131253 bayes_pls_golite062009
molecular transducer activity 1.24423621131253 bayes_pls_golite062009
protein complex binding 1.23240411516711 bayes_pls_golite062009
RNA binding 1.22339134958708 bayes_pls_golite062009
heparin binding 1.15897181987617 bayes_pls_golite062009
transcription factor activity 1.15427978494805 bayes_pls_golite062009
transcription activator activity 1.11465354227601 bayes_pls_golite062009
polysaccharide binding 1.09475063562581 bayes_pls_golite062009
transmembrane transporter activity 1.07075219961504 bayes_pls_golite062009
growth factor activity 0.850395354506359 bayes_pls_golite062009
pattern binding 0.83687933614214 bayes_pls_golite062009
substrate-specific transporter activity 0.801327928563072 bayes_pls_golite062009
mRNA binding 0.67699218614597 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.546870122670733 bayes_pls_golite062009
extracellular matrix structural constituent 0.52360080681204 bayes_pls_golite062009
calcium ion binding 0.416416901481401 bayes_pls_golite062009
receptor activity 0.376562682962271 bayes_pls_golite062009
hydrolase activity 0.374282208763552 bayes_pls_golite062009
monosaccharide binding 0.30021811359531 bayes_pls_golite062009
transmembrane receptor activity 0.213382263378401 bayes_pls_golite062009
structural constituent of cytoskeleton 0.160855218996334 bayes_pls_golite062009
growth factor binding 0.0922754536898114 bayes_pls_golite062009
cytokine binding 0.0273545648165503 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [422-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEADGLKSYQ KKVFDLLYKV ADISFLSAYK SKIMELIEKA ETQPNLTIGV LISIVIVFLS  60
   61 LFFKLIFGGA KAKVEKKKPE TAAETSTSEA KTEEKAEAVA APRKRQTRRE S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle