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View Structure Prediction Details

Protein: AROE_BACSU
Organism: Bacillus subtilis
Length: 280 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AROE_BACSU.

Description E-value Query
Range
Subject
Range
gi|170127636, gi... - gi|170707392|ref|ZP_02897846.1| shikimate 5-dehydrogenase [Bacillus anthracis str. A0389], gi|170127...
gi|21402380, gi|... - gi|65321706|ref|ZP_00394665.1| COG0169: Shikimate 5-dehydrogenase [Bacillus anthracis str. A2012], r...
gi|229268320, gi... - gi|229603912|ref|YP_002868624.1| shikimate dehydrogenase [Bacillus anthracis str. A0248], gi|2292683...
gi|47529857, gi|... - gi|47529857|ref|YP_021206.1| shikimate 5-dehydrogenase [Bacillus anthracis str. 'Ames Ancestor'], gi...
gi|30264406, gi|... - gi|30264406|ref|NP_846783.1| shikimate 5-dehydrogenase [Bacillus anthracis str. Ames], gi|30259064|g...
293.0 [0..1] [277..1]

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Predicted Domain #1
Region A:
Residues: [1-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKLYGVIGN PIGHSMSPDI HNASLKDLGL DGHYHAFKVE ENDLEDAVKG IRALGVQGIN  60
   61 VTVPHKVSIM DYLDHIDESA KVLGAVNTVR REGDKLVGYN TDGEGFVKSL MKVLDKPISE 120
  121 LSFLMIGAGG AARAIFTTFV RNTPKKFDIC NRTLEKAKRL TEATPSFHNK EVLSIKEAEE 180
  181 RLEQYDVIIH TTSVGMYPNV DDVPLSLQRA ASSAVVCDIV YNPIQTALLK EASQKGLKTL 240
  241 DGVGMFVEQA ALSFQLWTGQ EPNIEKMRSI VIGKLGGTEC 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.69897
Match: 1nvtA
Description: Shikimate 5-dehydrogenase AroE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
shikimate 5-dehydrogenase activity 3.40568087442781 bayes_pls_golite062009
malate dehydrogenase activity 3.18316725684556 bayes_pls_golite062009
malic enzyme activity 2.5718745582089 bayes_pls_golite062009
oxidoreductase activity 2.15129810845685 bayes_pls_golite062009
catalytic activity 2.0643953589843 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.43144163429682 bayes_pls_golite062009
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity 0.858327241653065 bayes_pls_golite062009
fatty acid synthase activity 0.714637370305282 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.39426299750207 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.192594057004213 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle