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View Structure Prediction Details

Protein: CE33866
Organism: Caenorhabditis elegans
Length: 431 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE33866.

Description E-value Query
Range		 Subject
Range
CE38987 - status:Confirmed UniProt:Q4A1S8 protein_id:CAJ21557.1
 422.0 [0..1] [431..2]

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Predicted Domain #1
Region A:
Residues: [1-431] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRALLNASR RVATVRSMAS TVEGDAFRLS EYSSKYLGHR KAAFTEKLEI VNADDTPALP  60
   61 IYRVTNAVGD VIDKSQDPNF DEQTSLKMYK TMTQLNIMDR ILYDSQRQGR ISFYMTSFGE 120
  121 EGNHVGSAAA LEPQDLIYGQ YREAGVLLWR GYTMENFMNQ CYGNADDLGK GRQMPMHFGT 180
  181 KERNFVTISS PLTTQLPQAV GSAYAFKQQK DNNRIAVVYF GDGAASEGDA HAAFNFAATL 240
  241 KCPIIFFCRN NGYAISTPTS EQYGGDGIAG KGPAYGLHTI RVDGNDLLAV YNATKEARRV 300
  301 ALTNRPVLIE AMTYRLGHHS TSDDSTAYRS SDEVQTWGDK DHPITRFKKY ITERGWWNEE 360
  361 KEMEWQKEVK KRVLTEFAAA EKRKKAHYHD LFEDVYDELP LRLRRQRDEL DAHVAEYKEH 420
  421 YPMLETLQSK P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.0
Match: 1x7yA
Description: Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
pyruvate dehydrogenase activity 11.3856674722026 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 11.0549577473177 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 10.8180381281695 bayes_pls_golite062009
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 7.00951713446616 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 6.25236550086321 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 4.89064211833637 bayes_pls_golite062009
acetolactate synthase activity 4.51986503762195 bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups 3.8269109174531 bayes_pls_golite062009
2-oxoisovalerate dehydrogenase (acylating) activity 3.00128844859152 bayes_pls_golite062009
cyclin-dependent protein kinase 5 activator regulator activity 3.00128844859152 bayes_pls_golite062009
catalytic activity 2.25537597692103 bayes_pls_golite062009
oxidoreductase activity 1.85833680148029 bayes_pls_golite062009
transketolase activity 1.53492491341322 bayes_pls_golite062009
protein binding 0.992849906276347 bayes_pls_golite062009
binding 0.750068469698571 bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0.667418924427388 bayes_pls_golite062009
pyruvate decarboxylase activity 0.198062360371269 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle