| Protein: | nhr-114 |
| Organism: | Caenorhabditis elegans |
| Length: | 418 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-114.
| Description | E-value | Query Range |
Subject Range |
|
|
301.0 | [0..2] | [418..51] |
|
Region A: Residues: [1-136] |
1 11 21 31 41 51
| | | | | |
1 MTPQSSPSSS RDHVCLVCQD FASGYHYGVP SCVGCKTFFR RTIMKKQKYI CQFEGNCPVD 60
61 KTIRCACRYC RFEKCLSVGM DRNALQQNRD PIGYTKRTRR PKKELKTTSD CSSDEGASTP 120
121 PSVSPLQLSP PPISPL
|
| Detection Method: |  |
| Confidence: | 24.522879 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [137-418] |
1 11 21 31 41 51
| | | | | |
1 LFQAAPLKPR RCILQTLAER EKCANDLRLS EYLPIRSLHE ALCSKALLND TAFLEKWGQP 60
61 SERHQIFDLR FVNHDDYHYW HERDWFLLTE YAKTFDVFEA LDYQDKAELV RHAAITVPVL 120
121 VQVWNSPDYG PDTIVFPDGA YFDRTPEPTR PAGLNRKKYQ MLDLVLKPFR DLQLDATEFA 180
181 AFKAVTFLNP DADISLPARK LVNNERVRIT KQLYGYMAMK DDVDTAIERF ARLVLMGTSM 240
241 SKMACESKEA VWIADFFENI GFSAFARQLF FGDTTSVVAH KL
|
| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| receptor activity | 2.07573173722434 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| molecular transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| signal transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
