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View Structure Prediction Details

Protein: rnh-1.0
Organism: Caenorhabditis elegans
Length: 251 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rnh-1.0.

Description E-value Query
Range
Subject
Range
gi|61372889 - gi|61372889|gb|AAX43931.1| ribonuclease H1 [synthetic construct]
236.0 [0..5] [246..26]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKNDQYYAV ARGKQVGIYR TWNECKTQID GFQNARFKKF ATEAEARKFV ADNMSVPGSK  60
   61 PVTPAVSTSS ATRKRTHEGT KFTEAKKMKT EEEVIDPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 2iajB
Description: No description for 2iajB was found.

Predicted Domain #2
Region A:
Residues: [99-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FANAPVVYTD GACSSNGTKN AKAGWGVYWG DDSEDNEFGP VYGAPTNNRG ELIAVQKAIE  60
   61 KAIEKRLPKV VIKTDSNLLV QSMNIWIHGW KRKGWKTSTG SEVLNQDVLM KIDNLRQKLK 120
  121 VKFLHVRGHA GIDGNEKADE LARKGAQMFI KRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1rbrA
Description: STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 5.30591758406946 bayes_pls_golite062009
exoribonuclease activity 3.71639182685131 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 3.59362615133405 bayes_pls_golite062009
3'-5'-exoribonuclease activity 3.1992647486402 bayes_pls_golite062009
exonuclease activity 3.13676176369406 bayes_pls_golite062009
nuclease activity 3.11657409772275 bayes_pls_golite062009
ribonuclease H activity 2.91966688044755 bayes_pls_golite062009
endonuclease activity 2.63074055051349 bayes_pls_golite062009
endoribonuclease activity 2.59247838057313 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.57498413015114 bayes_pls_golite062009
hydrolase activity 2.41899414621161 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2.04408785855894 bayes_pls_golite062009
DNA polymerase activity 1.82615627615268 bayes_pls_golite062009
DNA-directed DNA polymerase activity 1.68530265026203 bayes_pls_golite062009
3'-5' exonuclease activity 1.44123900197846 bayes_pls_golite062009
nucleotidyltransferase activity 1.28926675473754 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
binding 1.20709976964365 bayes_pls_golite062009
nucleic acid binding 1.12235348738959 bayes_pls_golite062009
deoxyribonuclease activity 1.1219517187744 bayes_pls_golite062009
transcription regulator activity 1.10433412699603 bayes_pls_golite062009
DNA binding 0.710663468386339 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.708753843279937 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.598360955770972 bayes_pls_golite062009
0.49473250705373 bayes_pls_golite062009
transcription factor activity 0.332903382446869 bayes_pls_golite062009
exodeoxyribonuclease activity 0.278838342302102 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.261428436029202 bayes_pls_golite062009
protein binding 0.242714557118293 bayes_pls_golite062009
structure-specific DNA binding 0.0701825322473915 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle