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View Structure Prediction Details

Protein: CE33172
Organism: Caenorhabditis elegans
Length: 695 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE33172.

Description E-value Query
Range
Subject
Range
gi|114586983 - gi|114586983|ref|XP_001167117.1| PREDICTED: RNA binding motif protein 5 isoform 1 [Pan troglodytes]
272.0 [0..1] [694..104]

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Predicted Domain #1
Region A:
Residues: [1-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNDVDNTKI TLSLGKCGYL PQDVRTMTKF DKNTKQIRTF AFVEFSNRET AEQWMTDYEG  60
   61 WLTLDDGRTL AVEYAKGDPA AGSGNKGDDW ICAHCSMNNF VKRQTCFKCE ISKDQSMELE 120
  121 KLGAHMVGMT PCDTLLIRGL PDGINNSLIF DSLGALVCLS SISMIKLSES KRFAYLQMKS 180
  181 ADEAKMLLNL TYKSPIRIKD KDVQVSWC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1po6A
Description: Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
protein binding 2.17260848225967 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.425042944899091 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
snoRNA binding 0.0568636182001701 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [209-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDSMSKLIQQ QMTMLTAGPG KNSVATGSLA QGNMTGAEIA AAALSKANAV RQASQQVGQI  60
   61 MTGLPAPAAN MIPPNFSVPP PNLSVPPPMQ ATQPEHQNGV IGMT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [313-520]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTPKGLLPRY LPPNPLTFAH DPNLGYYVDP ITKFCYDSAT GYYFNNATSQ WCNWDLTHHT  60
   61 YFPVETPAVI NSADPEEEKM KKNEEGPKTA QDLVKDMAKW AKRQEKDKKK VQISIKGKET 120
  121 KGIELKNVFS NEKQKRIAQT AALFDDDEEE DQEEEVRGRR SEEPSTSSSF SSVPLAPRKS 180
  181 TLQDVRDAME RALYDETKKT CMLCKRAF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [521-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDVEVLRKHV EKSDLHRNNL EAKRAEWGRE TAAKLQEEEE DASAPDLPKI VYRDRAKERR  60
   61 RQFGIDSTGY AFDVMGGPPG PTSVRHEETI RKVSEEASKR PLDESNIGNR LLKSMGWKEG 120
  121 QGVGKHAQGI VNPIEAERFV QGAGLGAAGS KMRHGAEASH KEKTRQALYS RYHDA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle