| Protein: | obr-3 |
| Organism: | Caenorhabditis elegans |
| Length: | 733 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for obr-3.
| Description | E-value | Query Range |
Subject Range |
|
|
743.0 | [0..8] | [733..45] |
|
Region A: Residues: [1-180] |
1 11 21 31 41 51
| | | | | |
1 MEEFDENSRK SLKKQKKEYR DEKKRVNDEL LSALRDPTVV VMADTLKIRG ALKRWNRYYC 60
61 VLKPGLLILY KHKKADRGDW VGTVLLNHCE LIERPSKKDG FCFKLFHPMD MSIWGNRGPL 120
121 GQSFGSFTLN PLNTSFLICR APSDQAGRCW MDALELSFKC TGLLKKTMNE LDDKNGDSSM 180
181
|
| Detection Method: |  |
| Confidence: | 31.0 |
| Match: | 1v88A |
| Description: | Solution Structure of the Pleckstrin Homology Domain of Oxysterol-Binding Protein-Related Protein 8 (KIAA1451 Protein) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.86147407357315 | bayes_pls_golite062009 |
| protein binding | 2.12168271674167 | bayes_pls_golite062009 |
| molecular transducer activity | 1.34134699517825 | bayes_pls_golite062009 |
| signal transducer activity | 1.34134699517825 | bayes_pls_golite062009 |
| transporter activity | 1.28986800087234 | bayes_pls_golite062009 |
| transcription regulator activity | 1.10315055505849 | bayes_pls_golite062009 |
| phospholipid binding | 1.09683218092034 | bayes_pls_golite062009 |
| receptor activity | 1.02045773197699 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.990048359575281 | bayes_pls_golite062009 |
| nucleic acid binding | 0.870327630723237 | bayes_pls_golite062009 |
| DNA binding | 0.856684960067851 | bayes_pls_golite062009 |
| receptor binding | 0.84825890337371 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.79883446648737 | bayes_pls_golite062009 |
| oxysterol binding | 0.792005176778139 | bayes_pls_golite062009 |
| clathrin binding | 0.768496041585918 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase signaling protein activity | 0.740468760397673 | bayes_pls_golite062009 |
| structural molecule activity | 0.731721560204237 | bayes_pls_golite062009 |
| phosphoinositide binding | 0.71817045430443 | bayes_pls_golite062009 |
| protein domain specific binding | 0.51731521446502 | bayes_pls_golite062009 |
| insulin receptor binding | 0.34801451897076 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.268141992393579 | bayes_pls_golite062009 |
| protein complex binding | 0.22543440052247 | bayes_pls_golite062009 |
| lipid binding | 0.179561240451969 | bayes_pls_golite062009 |
| SH2 domain binding | 0.13752708274522 | bayes_pls_golite062009 |
| hydrolase activity | 0.0955091952069367 | bayes_pls_golite062009 |
| actin binding | 0.0485598963526399 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.00282726023356339 | bayes_pls_golite062009 |
|
Region A: Residues: [181-248] |
1 11 21 31 41 51
| | | | | |
1 NDGQRDESRM SRDSDGDDTR ELAVSETDAE KHFQEIDDVQ DEDHEDGKMS ETSDTIREAF 60
61 TESAWIPS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [249-605] |
1 11 21 31 41 51
| | | | | |
1 PKEVFGPDGS LTEEVGEENK SLIWTLLKQI RPGMDLSKVV LPTFILEPRS FLEKLADYYY 60
61 HADLISEAVA EPDPFQRIVK VTKFFLSGFY KKPKGLKKPY NPILGETFRC KWEHPDGSTT 120
121 FYMAEQVSHH PPVSSLFITN RKAGFNISGT ILAKSKYYGN SLSAILAGKL RLTLLNLGET 180
181 YIVNLPYANC KGIMIGTMTM ELGGEVNIEC EKTGYRTTLD FKLKPMLGGA YNQIEGSIKY 240
241 GSDRLASIEG AWDGVIRIKG PDGKKELWNP TPEVIKTRLP RYEINMDEQG EWESAKLWRH 300
301 VTEAISNEDQ YKATEEKTAL ENDQRARAKS GIPHETKFFK KQHGDDYVYI HADYRPW
|
| Detection Method: | |
| Confidence: | 75.0 |
| Match: | 1zhtA |
| Description: | Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| oxysterol binding | 5.62675037461468 | bayes_pls_golite062009 |
| sterol binding | 4.18891468109664 | bayes_pls_golite062009 |
| 3.02967613614595 | bayes_pls_golite062009 | |
| steroid binding | 2.54679035876403 | bayes_pls_golite062009 |
| phosphoinositide binding | 2.2725849852584 | bayes_pls_golite062009 |
| binding | 2.10831141109811 | bayes_pls_golite062009 |
| phospholipid binding | 2.08170907241909 | bayes_pls_golite062009 |
| lipid binding | 1.8520231230392 | bayes_pls_golite062009 |
| cholesterol binding | 0.644339278395346 | bayes_pls_golite062009 |
|
Region A: Residues: [606-733] |
1 11 21 31 41 51
| | | | | |
1 DNNNDIQQIE NNYVVKTISR HSKRKTGNSE QLGSDNTSEA SESDEEVIEP KIKKKEIVPA 60
61 KSKPITPEVA DERIKEMERK FELAIRRMEA ANERQSSRTL NAIQSTLLFV FVVTSVVQSI 120
121 FMFFMLRK
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
