| Protein: | lin-45 |
| Organism: | Caenorhabditis elegans |
| Length: | 614 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lin-45.
| Description | E-value | Query Range |
Subject Range |
|
|
297.0 | [0..43] | [612..1] |
|
Region A: Residues: [1-90] |
1 11 21 31 41 51
| | | | | |
1 MSAMAVLYSV CHFHGGWNRR KSAPKSPVTS SQTPSSSSTR RRMSRINFKK SSASTTPTSP 60
61 HCPSPRLISL PRCASSSIDR KDQASPMASP
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [91-184] |
1 11 21 31 41 51
| | | | | |
1 STPLYPKHSD SLHSLSGHHS AGGAGTSDKE PPKFKYKMIM VHLPFDQHSR VEVRPGETAR 60
61 DAISKLLKKR NITPQLCHVN ASSDPKQESI ELSL
|
| Detection Method: | |
| Confidence: | 16.69897 |
| Match: | 1rrbA |
| Description: | THE RAS-BINDING DOMAIN OF RAF-1 FROM RAT, NMR, 1 STRUCTURE |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.35732272412639 | bayes_pls_golite062009 |
| protein binding | 1.86841453215444 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.63853240069891 | bayes_pls_golite062009 |
| kinase activity | 1.62384132584197 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.51475136357956 | bayes_pls_golite062009 |
| transferase activity | 1.25776281736571 | bayes_pls_golite062009 |
| protein kinase activity | 1.13077363367159 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.673589832597734 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.334601927012824 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.315664702789604 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.162163146322721 | bayes_pls_golite062009 |
| protein tag | 0.00311613478935058 | bayes_pls_golite062009 |
|
Region A: Residues: [185-285] |
1 11 21 31 41 51
| | | | | |
1 TMEEIASRLP GNELWVHSEY LNTVSSIKHA IVRRTFIPPK SCDVCNNPIW MMGFRCEFCQ 60
61 FKFHQRCSSF APLYCDLLQS VPKNEDLVKE LFGIASQVEG P
|
| Detection Method: | |
| Confidence: | 9.045757 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.36195429973813 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.10625597744594 | bayes_pls_golite062009 |
| kinase activity | 2.03632850156074 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.8531437045627 | bayes_pls_golite062009 |
| transferase activity | 1.4550521488922 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.39167263636091 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.37139209958305 | bayes_pls_golite062009 |
| protein kinase activity | 1.34251805835141 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.956859696337723 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.911061212692491 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.907368864863833 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.661240850692236 | bayes_pls_golite062009 |
| transcription regulator activity | 0.487499907025216 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
| nucleic acid binding | 0.0210137897362572 | bayes_pls_golite062009 |
|
Region A: Residues: [286-477] |
1 11 21 31 41 51
| | | | | |
1 DRSVAEIVLA NLAPTSGQSP AATPDSSHPD LTSIKRTGGV KRHPMAVSPQ NETSQLSPSG 60
61 PYPRDRSSSA PNINAINDEA TVQHNQRILD ALEAQRLEEE SRDKTGSLLS TQARHRPHFQ 120
121 SGHILSGARM NRLHPLVDCT PLGSNSPSST CSSPPGGLIG QPTLGQSPNV SGSTTSSLVA 180
181 AHLHTLPLTP PQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [478-614] |
1 11 21 31 41 51
| | | | | |
1 SAPPQKISPG FFRNRSRSPG ERLDAQRPRP PQKPHHEDWE ILPNEFIIQY KVGSGSFGTV 60
61 YRGEFFGTVA IKKLNVVDPT PSQMAAFKNE VAVLKKTRHL NVLLFMGWVR EPEIAIITQW 120
121 CEGSSLYRHI HVQGDLN
|
| Detection Method: | |
| Confidence: | 22.69897 |
| Match: | 2fb8A |
| Description: | No description for 2fb8A was found. |
