| Protein: | wwp-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 792 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wwp-1.
| Description | E-value | Query Range |
Subject Range |
|
|
593.0 | [0..1] | [792..1] |
|
Region A: Residues: [1-188] |
1 11 21 31 41 51
| | | | | |
1 MARNEPSSQQ PSSSGSNGTP AQQNGSAKPS KVTVKVVNAS FTKAADCYVE ITSDTSSAAP 60
61 KKTTVKKKTM APEWNEHLNV HANESSTISF RLLQKAKLFD DTCLGMAKLK LSSLTRNENG 120
121 EFKNDINNIS LLAKDSSKIG TLNIIFSGYP ERKRRSAGVR AETAASASSE ASTSNGVATS 180
181 SSARRPAT
|
| Detection Method: |  |
| Confidence: | 22.39794 |
| Match: | 2nsqA |
| Description: | No description for 2nsqA was found. |
|
Region A: Residues: [189-312] |
1 11 21 31 41 51
| | | | | |
1 AKRDTLAAPT STAAAAAAAT AGGTPAAGAE EQLPDGWEMR FDQYGRKYYV DHTTKSTTWE 60
61 RPSTQPLPQG WEMRRDPRGR VYYVDHNTRT TTWQRPTADM LEAHEQWQSG RDQAMLQWEQ 120
121 RFLL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [313-412] |
1 11 21 31 41 51
| | | | | |
1 QQNNFSADDP LGPLPEGWEK RQDPNTSRMY FVNHVNRTTQ WEDPRTQGGS DQPLPDGWEM 60
61 RFTEQGVPFF IDHQSKTTTY NDPRTGKPVG PLGVVGVQMA
|
| Detection Method: | |
| Confidence: | 3.11 |
| Match: | 1tk7A |
| Description: | NMR structure of WW domains (WW3-4) from Suppressor of Deltex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.13196227814032 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 2.50663692075518 | bayes_pls_golite062009 |
| transcription regulator activity | 2.38996385458463 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 2.33627990300135 | bayes_pls_golite062009 |
| transcription activator activity | 1.7271283334564 | bayes_pls_golite062009 |
| transcription factor binding | 1.70374758907671 | bayes_pls_golite062009 |
| histone methyltransferase activity | 1.67021314973391 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.64250861692227 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.5022756775252 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.33590567799099 | bayes_pls_golite062009 |
| protein binding | 1.27041711914941 | bayes_pls_golite062009 |
| protein methyltransferase activity | 0.9455445085372 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 0.863094487787088 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 0.863094487787088 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 0.863094487787088 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 0.539489048525578 | bayes_pls_golite062009 |
| catalytic activity | 0.231344568578849 | bayes_pls_golite062009 |
| transcription repressor activity | 0.179456065780754 | bayes_pls_golite062009 |
|
Region A: Residues: [413-792] |
1 11 21 31 41 51
| | | | | |
1 MEKSFRWKIA QFRYLCLSNS VPNHVKITVS RNNVFEDSFQ EIMRKNAVDL RRRLYIQFRG 60
61 EEGLDYGGVA REWFFLLSHE VLNPMYCLFM YAGNNNYSLQ INPASFVNPD HLKYFEYIGR 120
121 FIAMALFHGK FIYSGFTMPF YKKMLNKKIV LKDIEQVDSE IYNSLMWIKD NNIDECDMEL 180
181 YFVADYELLG ELKTYELKEG GTEIAVTEEN KLEYIELLVE WRFNRGVEQQ TKAFFTGFNS 240
241 VFPLEWMQYF DERELELLLC GMQDVDVDDW QRNTVYRHYA PQSKQVTWFW QWVRSLDQEK 300
301 RARLLQFVTG TCRVPVGGFS ELMGSTGPQL FCIERVGKEN WLPRSHTCFN RLDLPPYRSY 360
361 DQLVEKLSMA IEMTEGFGNE
|
| Detection Method: | |
| Confidence: | 124.0 |
| Match: | 1nd7A |
| Description: | Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 7.14616396317218 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 6.99796579811325 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 6.03005793772151 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 4.50502148129705 | bayes_pls_golite062009 |
| sodium channel inhibitor activity | 3.64966529121446 | bayes_pls_golite062009 |
| binding | 3.09019421479054 | bayes_pls_golite062009 |
| ion channel inhibitor activity | 2.14402963004533 | bayes_pls_golite062009 |
| channel inhibitor activity | 2.14402963004533 | bayes_pls_golite062009 |
| ligase activity | 1.85936914071714 | bayes_pls_golite062009 |
| transcription regulator activity | 1.53041428769512 | bayes_pls_golite062009 |
| nucleic acid binding | 1.45373137371678 | bayes_pls_golite062009 |
| DNA binding | 1.32990029553036 | bayes_pls_golite062009 |
| protein binding | 1.29390544644063 | bayes_pls_golite062009 |
| sodium channel regulator activity | 1.19047973745862 | bayes_pls_golite062009 |
| catalytic activity | 1.15152367676155 | bayes_pls_golite062009 |
| transcription factor binding | 0.558655949211634 | bayes_pls_golite062009 |
| ubiquitin-ubiquitin ligase activity | 0.373649200425601 | bayes_pls_golite062009 |
| channel regulator activity | 0.072778668515899 | bayes_pls_golite062009 |
| 0.051942165438844 | bayes_pls_golite062009 |
